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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1953 2
1954 2
1955 2
1956 2
1957 1
1958 2
1966 1
1967 1
1968 1
1969 1
1972 1
1973 1
1975 3
1977 1
1979 1
1980 5
1981 5
1982 6
1983 3
1984 8
1985 7
1986 6
1987 9
1988 3
1989 11
1990 10
1991 23
1992 21
1993 31
1994 22
1995 30
1996 25
1997 35
1998 38
1999 39
2000 33
2001 47
2002 34
2003 33
2004 52
2005 45
2006 93
2007 82
2008 70
2009 85
2010 86
2011 112
2012 91
2013 93
2014 111
2015 154
2016 126
2017 157
2018 127
2019 113
2020 117
2021 110
2022 97
2023 88
2024 32

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2,317 results

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Page 1
Short-Term Symptomatic Relief in Gastroesophageal Reflux Disease: A Comparative Study of Esomeprazole and Vonoprazan.
Sakurai K, Suda H, Fujie S, Takeichi T, Okuda A, Murao T, Hasuda K, Hirano M, Ito K, Tsuruta K, Hattori M. Sakurai K, et al. Dig Dis Sci. 2019 Mar;64(3):815-822. doi: 10.1007/s10620-018-5365-0. Epub 2018 Nov 10. Dig Dis Sci. 2019. PMID: 30415407 Free PMC article. Clinical Trial.
Sixty patients were randomly assigned to either the esomeprazole group (n = 30) or the vonoprazan group (n = 30). Treatment response rates in each drug group were evaluated according to the GerdQ. ...
Sixty patients were randomly assigned to either the esomeprazole group (n = 30) or the vonoprazan group (n = 30). Treatment re …
Steps toward Rationalization of the Enantiomeric Excess of the Sakurai-Hosomi-Denmark Allylation Catalyzed by Biisoquinoline N,N'-Dioxides Using Computations.
Morgante P, Deluca C, Jones TE, Aldrich GJ, Takenaka N, Peverati R. Morgante P, et al. Catalysts. 2021 Dec;11(12):1487. doi: 10.3390/catal11121487. Epub 2021 Dec 4. Catalysts. 2021. PMID: 36311901 Free PMC article.
In this work, we focus on the full computational characterization of the catalytic activity of substituted biisoquinoline-N,N'-dioxides for the allylation of 2-naphthaldehyde. We characterized the structure of all transition states as well as identified the pi stack …
In this work, we focus on the full computational characterization of the catalytic activity of substituted biisoquinoline-N,N' …
3-(2,3,5,6,7,8-Hexahydro-1H-cyclo-penta-[b]quinolin-9-yl)-1,5-bis-(4-methoxy-phen-yl)biuret.
Sakurai K, Noguchi K, Nishibe K. Sakurai K, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Feb 20;66(Pt 3):o655. doi: 10.1107/S1600536810006057. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21580406 Free PMC article.
Ipidacrine (2,3,5,6,7,8-hexa-hydro-1H-cyclo-penta-[b]quinolin-9-amine) was reacted with 4-methoxy-phenyl isocyanate to give the title compound, C(28)H(30)N(4)O(4). An intra-molecular N-HO hydrogen bond results in an essentially planar [r.m.s. deviation from the mean …
Ipidacrine (2,3,5,6,7,8-hexa-hydro-1H-cyclo-penta-[b]quinolin-9-amine) was reacted with 4-methoxy-phenyl isocyanate to give the title compou …
Molecular dissection of cognition, emotion and thoughts.
Sakurai T, Sawa A. Sakurai T, et al. Semin Cell Dev Biol. 2022 Sep;129:1-2. doi: 10.1016/j.semcdb.2022.05.018. Epub 2022 May 30. Semin Cell Dev Biol. 2022. PMID: 35654664 No abstract available.
Axial-Chiral Biisoquinoline N, N'-Dioxides Bearing Polar Aromatic C-H Bonds as Catalysts in Sakurai-Hosomi-Denmark Allylation.
Reep C, Morgante P, Peverati R, Takenaka N. Reep C, et al. Org Lett. 2018 Sep 21;20(18):5757-5761. doi: 10.1021/acs.orglett.8b02457. Epub 2018 Sep 10. Org Lett. 2018. PMID: 30199262
Lewis bases containing the 3,5-bis(trifluoromethyl)phenyl group were found to be significantly more enantioselective for a wider range of substrates than those bearing aromatic residues that are not strongly electron-deficient in the allylation of aldehydes with allyltrichlorosil …
Lewis bases containing the 3,5-bis(trifluoromethyl)phenyl group were found to be significantly more enantioselective for a wider range of su …
A commentary on Hamanaka, T., Chin, S., Shinmei, Y., Sakurai, T., Tanito, M., Kijima, R., Tsutsui, A., Ueno, Y., Ishida, N., Ueda, T., Kumasaka, T. (2022) Histological analysis of trabeculotomy- An investigation on the intraocular pressure lowering mechanism. Exp. Eye Res. 219:109079. https://doi.org/10.1016/j.exer.2022.109079.
Sabur H, Baykara M. Sabur H, et al. Exp Eye Res. 2022 Nov;224:109246. doi: 10.1016/j.exer.2022.109246. Epub 2022 Sep 15. Exp Eye Res. 2022. PMID: 36115579 No abstract available.
Interruption of Formal Schmidt Rearrangement/Hosomi-Sakurai Reaction of Vinyl Azides with Allyl/Propargylsilanes.
Fang G, Liu Z, Cao S, Yuan H, Zhang J, Pan L. Fang G, et al. Org Lett. 2018 Nov 16;20(22):7113-7116. doi: 10.1021/acs.orglett.8b03062. Epub 2018 Nov 2. Org Lett. 2018. PMID: 30387360
An interrupted Schmidt rearrangement/Hosomi-Sakurai reaction of N-tosyl and S-substituted vinyl azides is reported. With BF(3).Et(2)O as a Lewis acid promoter, the denitrogenative fragmentation of vinyl azides facilitates the generation of the N/ S-stabilized …
An interrupted Schmidt rearrangement/Hosomi-Sakurai reaction of N-tosyl and S-substituted vinyl azides is reported. With BF(3) …
Asymmetric, anti-selective scandium-catalyzed Sakurai additions to glyoxyamide. Applications to the syntheses of N-boc D-alloisoleucine and D-isoleucine.
Evans DA, Aye Y, Wu J. Evans DA, et al. Org Lett. 2006 May 11;8(10):2071-3. doi: 10.1021/ol0604771. Org Lett. 2006. PMID: 16671784
[reaction: see text] An enantio- and diastereoselective Sakurai-Hosomi reaction, catalyzed by chiral scandium pyridyl-bis(oxazoline) (pybox) complexes, has been developed. Both alkyl- and aryl-substituted allylsilanes are effective coupling partners with N-phenylgly …
[reaction: see text] An enantio- and diastereoselective Sakurai-Hosomi reaction, catalyzed by chiral scandium pyridyl-bis(oxazoline) …
ZnO-based ultraviolet photodetectors.
Liu K, Sakurai M, Aono M. Liu K, et al. Sensors (Basel). 2010;10(9):8604-34. doi: 10.3390/s100908604. Epub 2010 Sep 17. Sensors (Basel). 2010. PMID: 22163675 Free PMC article. Review.
ZnO-based photoconductors, Schottky photodiodes, metal-semiconductor-metal photodiodes and p-n junction photodetectors have been developed. In this work, it mainly focuses on the ZnO and ZnMgO films photodetectors. ...
ZnO-based photoconductors, Schottky photodiodes, metal-semiconductor-metal photodiodes and p-n junction photodetectors have been deve …
N-demethylation and N-oxidation of imipramine in rat thoracic aortic endothelial cells.
Ueda Y, Yaginuma T, Sakurai E, Sakurai E. Ueda Y, et al. In Vitro Cell Dev Biol Anim. 2014 Jun;50(6):496-501. doi: 10.1007/s11626-014-9739-0. Epub 2014 Mar 20. In Vitro Cell Dev Biol Anim. 2014. PMID: 24647745 Free PMC article.
The aim of this study was to examine whether cultured rat thoracic aortic endothelial cells (TAECs) have the ability to metabolize the tertiary amine, imipramine. In rat TAECs, imipramine was biotransformed into N-demethylate and N-oxide by cytochrome P450 (CYP) and …
The aim of this study was to examine whether cultured rat thoracic aortic endothelial cells (TAECs) have the ability to metabolize the terti …
2,317 results