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Page 1
N-(2,5-Dimeth-oxy-phen-yl)-6-nitro-quinazolin-4-amine.
Saad SM, Khan I, Perveen S, Khan KM, Yousuf S. Saad SM, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o8. doi: 10.1107/S1600536812048878. Epub 2012 Dec 5. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23476461 Free PMC article.
N-Aryl-3,4-dihydroisoquinoline Carbothioamide Analogues as Potential Urease Inhibitors.
Ali F, Shamim S, Lateef M, Khan KM, Taha M, Salar U, Wadood A, Rehman AU, Nawaz NUA, Perveen S. Ali F, et al. ACS Omega. 2021 Jun 7;6(24):15794-15803. doi: 10.1021/acsomega.1c01182. eCollection 2021 Jun 22. ACS Omega. 2021. PMID: 34179623 Free PMC article.
N-Aryl-3,4-dihydroisoquinoline carbothioamide analogues 1-22 were synthesized by a simple one-step reaction protocol and subjected to in vitro urease inhibition studies for the first time. ...
N-Aryl-3,4-dihydroisoquinoline carbothioamide analogues 1-22 were synthesized by a simple one-step reaction protocol and subjected to …
N'-(3-Chloro-benzyl-idene)-4-hy-droxy-benzohydrazide.
Saad SM, Fatima I, Perveen S, Khan KM, Yousuf S. Saad SM, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3499. doi: 10.1107/S1600536812048325. Epub 2012 Nov 30. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 23476306 Free PMC article.
The mol-ecule of the title compound, C14H11ClN2O2 adopts an E conformation of the azomethine double bond and the dihedral angle between the benzene rings is 38.96 (13). In the crystal, mol-ecules are linked by N-HO and O-HO (with the ketone O atom as acceptor) and C-HO (wi …
The mol-ecule of the title compound, C14H11ClN2O2 adopts an E conformation of the azomethine double bond and the dihedral angle between the …
2-(1H-Benzimidazol-2-yl)-N-[(E)-(dimethyl-amino)-methyl-idene]benzene-sulfonamide.
Ashraf A, Tahir MN, Siddiqui WA, Perveen N. Ashraf A, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2069. doi: 10.1107/S1600536812025159. Epub 2012 Jun 13. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22807890 Free PMC article.
The asymmetric unit of the title compound, C(16)H(16)N(4)O(2)S, contains two mol-ecules (A and B) with similar conformations: the benzene rings are oriented at dihedral angles of 80.94 (10) and 84.54 (10) with their adjacent 1H-benzimidazole groups. In the crystal, the mol …
The asymmetric unit of the title compound, C(16)H(16)N(4)O(2)S, contains two mol-ecules (A and B) with similar conformations: the ben …
2-{[(Dimethyl-amino)-methyl-idene]amino}-5-nitro-benzonitrile.
Saad SM, Haider SM, Perveen S, Khan KM, Yousuf S. Saad SM, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 1;69(Pt 1):o75. doi: 10.1107/S1600536812048866. Epub 2012 Dec 12. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23476456 Free PMC article.
The title mol-ecule, C10H10N4O2, is almost planar and adopts an E configuration of the azomethine [C=N = 1.298 (2) A] double bond. The benzene ring is attached to an essentially planar (r.m.s. deviation = 0.0226 A) amidine moiety (N=CN/Me2), the dihedral angle betwe …
The title mol-ecule, C10H10N4O2, is almost planar and adopts an E configuration of the azomethine [C=N = 1.298 (2) A] double bond. Th …
MIR204 n.37C>T variant as a cause of chorioretinal dystrophy variably associated with iris coloboma, early-onset cataracts and congenital glaucoma.
Jedlickova J, Vajter M, Barta T, Black GCM, Perveen R, Mares J, Fichtl M, Kousal B, Dudakova L, Liskova P. Jedlickova J, et al. Clin Genet. 2023 Oct;104(4):418-426. doi: 10.1111/cge.14391. Epub 2023 Jun 15. Clin Genet. 2023. PMID: 37321975
Four members of a three-generation Czech family with early-onset chorioretinal dystrophy were shown to be heterozygous carriers of the n.37C>T in MIR204. The identification of this previously reported pathogenic variant confirms the existence of a distinct clinical enti …
Four members of a three-generation Czech family with early-onset chorioretinal dystrophy were shown to be heterozygous carriers of the n …
First Report of Lavender Wilt Caused by Fusarium sporotrichioides in Croatia.
Cosic J, Vrandecic K, Jurkovic D, Postic J, Orzali L, Riccioni L. Cosic J, et al. Plant Dis. 2012 Apr;96(4):591. doi: 10.1094/PDIS-12-11-1046-PDN. Plant Dis. 2012. PMID: 30727410
Blackwell Publishing Professional, Hoboken, NJ, 2006. (2) K. O'Donnell et al. Appl Biol. Sci. 95:2044, 1998. (3) K. Perveen and N. Bokhari. Plant Dis. 94:1163, 2010. (4) Y. Z. Ren et al. ...
Blackwell Publishing Professional, Hoboken, NJ, 2006. (2) K. O'Donnell et al. Appl Biol. Sci. 95:2044, 1998. (3) K. Perveen and N …
Frequency and Complications of Ileostomy.
Mehboob A, Perveen S, Iqbal M, Moula Bux K, Waheed A. Mehboob A, et al. Cureus. 2020 Oct 29;12(10):e11249. doi: 10.7759/cureus.11249. Cureus. 2020. PMID: 33274131 Free PMC article.
Result A total of 84 patients who received ileostomies were included in the study. Most patients were male (n=62; 73.8%), and 22 were female (26.19%). Of the 84 patients in our study, 34 (40.48%) had tuberculous intestine, 23 (27.38%) had typhoid ileal perforation, 23 (27. …
Result A total of 84 patients who received ileostomies were included in the study. Most patients were male (n=62; 73.8%), and 22 were …
Pd(II) complexes with chelating N-(1-alkylpyridin-4(1H)-ylidene)amide (PYA) ligands: Synthesis, characterization and evaluation of anticancer activity.
Zafar MN, Butt AM, Chaudhry GE, Perveen F, Nazar MF, Masood S, Dalebrook AF, Mughal EU, Sumrra SH, Sung YY, Muhammad TST, Wright LJ. Zafar MN, et al. J Inorg Biochem. 2021 Nov;224:111590. doi: 10.1016/j.jinorgbio.2021.111590. Epub 2021 Aug 24. J Inorg Biochem. 2021. PMID: 34507110
The bidentate N-(1-Alkylpyridin-4(1H)-ylidene)amide (PYA) pro-ligands [H(2)L(Bn)][Cl](2) (2), and [H(2)L(Me)][TfO](2) (3) were prepared by simple alkylation reactions of the known compound, N,N-di(pyridin-4-yl)oxalamide (H(2)L, 1). ...
The bidentate N-(1-Alkylpyridin-4(1H)-ylidene)amide (PYA) pro-ligands [H(2)L(Bn)][Cl](2) (2), and [H(2)L(Me)][TfO](2) (3) were prepar …
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.
Kimani SW, Perveen S, Szewezyk M, Zeng H, Dong A, Li F, Ghiabi P, Li Y, Chau I, Arrowsmith CH, Barsyte-Lovejoy D, Santhakumar V, Vedadi M, Halabelian L. Kimani SW, et al. Commun Biol. 2023 Dec 16;6(1):1272. doi: 10.1038/s42003-023-05655-8. Commun Biol. 2023. PMID: 38104184 Free PMC article.
Using a suite of biophysical and cellular assays, we confirm potent binding of C7683 (an analogue of Nx-1607) to the full-length Cbl-b and its N-terminal fragment containing the TKBD-LHR-RING domains. To further elucidate its mechanism of inhibition, we determined the co-c …
Using a suite of biophysical and cellular assays, we confirm potent binding of C7683 (an analogue of Nx-1607) to the full-length Cbl-b and i …
157 results