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Molecular disruption of DNA polymerase β for platinum sensitisation and synthetic lethality in epithelial ovarian cancers.
Ali R, Alblihy A, Miligy IM, Alabdullah ML, Alsaleem M, Toss MS, Algethami M, Abdel-Fatah T, Moseley P, Chan S, Mongan NP, Narayan S, Rakha EA, Madhusudan S. Ali R, et al. Among authors: alabdullah ml. Oncogene. 2021 Apr;40(14):2496-2508. doi: 10.1038/s41388-021-01710-y. Epub 2021 Mar 5. Oncogene. 2021. PMID: 33674744 Free PMC article.
Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.
Ali R, Alabdullah M, Algethami M, Alblihy A, Miligy I, Shoqafi A, Mesquita KA, Abdel-Fatah T, Chan SY, Chiang PW, Mongan NP, Rakha EA, Tomkinson AE, Madhusudan S. Ali R, et al. Among authors: alabdullah m. Theranostics. 2021 Jul 25;11(17):8350-8361. doi: 10.7150/thno.51456. eCollection 2021. Theranostics. 2021. PMID: 34373746 Free PMC article.