Biatrial myxoma and cerebral ischemia successfully treated with intravenous thrombolytic therapy and surgical resection

Tex Heart Inst J. 2008;35(2):193-5.

Abstract

We report what we believe is the 1st case in the medical literature in which an intravenous thrombolytic agent was used successfully--without massive intracranial bleeding--to treat acute stroke induced by atrial myxoma. Our patient, who had biatrial myxomas with a dual blood supply from the right coronary artery, presented with cerebral ischemia. Transesophageal echocardiography was essential in clarifying the diagnosis and in helping to direct surgical treatment.

Keywords: Cerebrovascular accident; echocardiography, transesophageal; embolism; heart atria/surgery; heart neoplasms/complications/diagnosis/surgery; intracranial embolism and thrombosis/etiology/drug therapy; myxoma; thrombolytic therapy; tissue plasminogen activator.

Publication types

  • Case Reports

MeSH terms

  • Brain Ischemia / diagnosis
  • Brain Ischemia / drug therapy*
  • Brain Ischemia / etiology
  • Fibrinolytic Agents / therapeutic use*
  • Heart Atria
  • Heart Neoplasms / pathology
  • Heart Neoplasms / surgery*
  • Humans
  • Male
  • Middle Aged
  • Myxoma / pathology
  • Myxoma / surgery*
  • Stroke / diagnosis
  • Stroke / drug therapy
  • Stroke / etiology
  • Thrombolytic Therapy*
  • Tissue Plasminogen Activator / therapeutic use*

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator