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Page 1
Antiplasmodial, Trypanocidal, and Genotoxicity In Vitro Assessment of New Hybrid α,α-Difluorophenylacetamide-statin Derivatives.
Araujo-Lima CF, de Cassia Castro Carvalho R, Rosario SL, Leite DI, Aguiar ACC, de Souza Santos LV, de Araujo JS, Salomão K, Kaiser CR, Krettli AU, Bastos MM, Aiub CAF, de Nazaré Correia Soeiro M, Boechat N, Felzenszwalb I. Araujo-Lima CF, et al. Among authors: bastos mm. Pharmaceuticals (Basel). 2023 May 24;16(6):782. doi: 10.3390/ph16060782. Pharmaceuticals (Basel). 2023. PMID: 37375730 Free PMC article.
(Phenylamino)pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia.
Pimentel LCF, Hoelz LVB, Canzian HF, Branco FSC, de Oliveira AP, Campos VR, Júnior FPS, Dantas RF, Resende JALC, Cunha AC, Boechat N, Bastos MM. Pimentel LCF, et al. Among authors: bastos mm. Beilstein J Org Chem. 2021 Sep 1;17:2260-2269. doi: 10.3762/bjoc.17.144. eCollection 2021. Beilstein J Org Chem. 2021. PMID: 34621389 Free PMC article.
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19.
Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Da Silva APD, Dias SDSG, da Silva CDS, Ferreira AC, Mattos M, Pão CRR, de Freitas CS, Soares VC, Hoelz LVB, Fernandes TVA, Branco FSC, Bastos MM, Boechat N, Saraiva FB, Ferreira MA, Jockusch S, Wang X, Tao C, Chien M, Xie W, Patel D, Garzia A, Tuschl T, Russo JJ, Rajoli RKR, Pedrosa CSG, Vitória G, Souza LRQ, Goto-Silva L, Guimarães MZ, Rehen SK, Owen A, Bozza FA, Bou-Habib DC, Ju J, Bozza PT, Souza TML. Sacramento CQ, et al. Among authors: bastos mm. J Antimicrob Chemother. 2021 Jun 18;76(7):1874-1885. doi: 10.1093/jac/dkab072. J Antimicrob Chemother. 2021. PMID: 33880524 Free PMC article.
New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations.
Leite DI, Fontes FV, Bastos MM, Hoelz LVB, Bianco MDCAD, de Oliveira AP, da Silva PB, da Silva CF, Batista DDGJ, da Gama ANS, Peres RB, Villar JDF, Soeiro MNC, Boechat N. Leite DI, et al. Among authors: bastos mm. Chem Biol Drug Des. 2018 Sep;92(3):1670-1682. doi: 10.1111/cbdd.13333. Epub 2018 Jun 13. Chem Biol Drug Des. 2018. PMID: 29745048
In silico and in vitro assessment of anti-Trypanosoma cruzi efficacy, genotoxicity and pharmacokinetics of pentasubstituted pyrrolic Atorvastatin-aminoquinoline hybrid compounds.
Araujo-Lima CF, Carvalho RCC, Peres RB, Fiuza LFA, Galvão BVD, Castelo-Branco FS, Bastos MM, Boechat N, Felzenszwalb I, Soeiro MNC. Araujo-Lima CF, et al. Among authors: bastos mm. Acta Trop. 2023 Jun;242:106924. doi: 10.1016/j.actatropica.2023.106924. Epub 2023 Apr 8. Acta Trop. 2023. PMID: 37037291