Maternal and perinatal outcome of eclampsia over a decade at a tertiary hospital in Kuwait

J Matern Fetal Neonatal Med. 2016 Oct;29(19):3132-7. doi: 10.3109/14767058.2015.1114095. Epub 2015 Nov 30.

Abstract

Aims: To determine maternal and perinatal outcome of eclampsia patients over a decade.

Methods: Analysis of case records of all eclampsia cases from January 2005 to December 2014.

Results: There were 30 cases of eclampsia. The most significant risk factors for developing pre-eclampsia are unbooked cases (97%), nulliparity, young age, marriage ≤4 months, history of pre-eclampsia in previous pregnancy, remarriage, preexisting diabetes mellitus, interval between pregnancies ≥10 years, positive family history. The incidence of eclampsia was 0.05%, antepartum eclampsia 15 (50%), intrapartum 6 (20%) and postpartum 9 (30%) with no maternal deaths, and 1 perinatal death. Perinatal mortality was 33.3/1000. 22 (73%) patients received magnesium sulphate (MgSO4) and 8 patients (27%) received Diazepam, of which 1 had recurrence of convulsions. All 15 antepartum cases were delivered by cesarean section as were 2 intrapartum. 13 (43%) of women delivered vaginally. Only 6 (20%) patients were of low socio-economic status and were primary school educated. Severe maternal complications occurred in 8 (27%), with abruptio placentae being the most common 3 (38%).

Conclusions: Incidence of eclampsia was low, with no maternal deaths. MgSO4 was found to be highly effective. Lack of antenatal care is a major risk factor.

Keywords: Antenatal care; magnesium sulphate; risk factors.

MeSH terms

  • Adolescent
  • Adult
  • Anticonvulsants / therapeutic use
  • Diazepam / therapeutic use
  • Female
  • Humans
  • Incidence
  • Infant, Newborn
  • Kuwait / epidemiology
  • Longitudinal Studies
  • Magnesium Sulfate / therapeutic use
  • Maternal Mortality
  • Perinatal Mortality*
  • Pre-Eclampsia / epidemiology*
  • Pre-Eclampsia / mortality
  • Pregnancy
  • Prenatal Care
  • Retrospective Studies
  • Risk Factors
  • Seizures / drug therapy
  • Young Adult

Substances

  • Anticonvulsants
  • Magnesium Sulfate
  • Diazepam