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Estimating Maximal In Vitro Skin Permeation Flux from Studies Using Non-sink Receptor Phase Conditions.
Yousef S, Liu X, Mostafa A, Mohammed Y, Grice JE, Anissimov YG, Sakran W, Roberts MS. Yousef S, et al. Pharm Res. 2016 Sep;33(9):2180-94. doi: 10.1007/s11095-016-1955-8. Epub 2016 Jun 16. Pharm Res. 2016. PMID: 27312087
PURPOSE: This study explored the impact of non-sink receptor conditions on the in vitro skin permeation test (IVPT) and sought to estimate equivalent sink condition IVPT data. ...The markedly lower steady - state fluxes found for the other two phases in which ethyl …
PURPOSE: This study explored the impact of non-sink receptor conditions on the in vitro skin permeation test (IVPT) and sought to est …