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Relationship Between Preexisting Cardiovascular Disease and Death and Cardiovascular Outcomes in Critically Ill Patients With COVID-19.
Vasbinder A, Meloche C, Azam TU, Anderson E, Catalan T, Shadid H, Berlin H, Pan M, O'Hayer P, Padalia K, Blakely P, Khaleel I, Michaud E, Huang Y, Zhao L, Pop-Busui R, Gupta S, Eagle K, Leaf DE, Hayek SS; STOP-COVID Investigators‡. Vasbinder A, et al. Circ Cardiovasc Qual Outcomes. 2022 Oct;15(10):e008942. doi: 10.1161/CIRCOUTCOMES.122.008942. Epub 2022 Oct 4. Circ Cardiovasc Qual Outcomes. 2022. PMID: 36193749 Free PMC article.
Methyl jasmonate elicitation effect on the metabolic profile of cambial meristematic cells culture derived from sweet basil (Ocimum basilicum L.) in relation to antioxidant activity: Untargeted metabolomics study in a time-based approach.
Zayed A, Farag MA, Mehring A, Salem MA, Ibrahim RM, Alseekh S, Fernie AR, Ulber R. Zayed A, et al. Phytochemistry. 2023 Sep;213:113777. doi: 10.1016/j.phytochem.2023.113777. Epub 2023 Jun 28. Phytochemistry. 2023. PMID: 37385363
The results revealed a stress response in primary metabolism manifested by an increase in amino and organic acids reaching their maximum levels after 48 (1.3-fold) and 72 (1.7-fold) h, respectively. In addition, phenolic acids (e.g., sagerinic acid, rosmarinic acid, …
The results revealed a stress response in primary metabolism manifested by an increase in amino and organic acids reaching their maximum lev …
Chitosan-sulfonic acid-catalyzed green synthesis of naphthalene-based azines as potential anticancer agents.
Alzahrani AY, Gomha SM, Zaki ME, Farag B, Abdelgawad FE, Mohamed MA. Alzahrani AY, et al. Future Med Chem. 2024 Apr;16(7):647-663. doi: 10.4155/fmc-2023-0351. Epub 2024 Feb 22. Future Med Chem. 2024. PMID: 38385167
Aim: This study focuses on advancing green chemistry in anticancer drug discovery, particularly through the synthesis of azine derivatives with a naphthalene core using CS-SO(3)H as a catalyst. Methods: Novel benzaldazine and ketazine derivatives were synthesized using ( …
Aim: This study focuses on advancing green chemistry in anticancer drug discovery, particularly through the synthesis of azine derivatives w …
Assessment of in-country capacity to maintain communicable disease surveillance and response services after polio eradication-Somalia.
Hsu CH, Harvey B, Mohamed A, Elfakki E, Ehrhardt D, Farag NH. Hsu CH, et al. Vaccine. 2020 Jan 29;38(5):1220-1224. doi: 10.1016/j.vaccine.2019.11.008. Epub 2019 Nov 18. Vaccine. 2020. PMID: 31753675 Free PMC article.
In addition, the polio program has been supporting a range of communicable disease surveillance, basic health services (e.g. routine immunizations) as well as emergency response activities (e.g. outbreak response). ...
In addition, the polio program has been supporting a range of communicable disease surveillance, basic health services (e.g. routine …
Performance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States.
Jezmir JL, Bharadwaj M, Chaitoff A, Diephuis B, Crowley CP, Kishore SP, Goralnick E, Merriam LT, Milliken A, Rhee C, Sadovnikoff N, Shah SB, Gupta S, Leaf DE, Feldman WB, Kim EY; STOP-COVID Investigators. Jezmir JL, et al. Cell Rep Med. 2021 Sep 21;2(9):100376. doi: 10.1016/j.xcrm.2021.100376. Epub 2021 Jul 28. Cell Rep Med. 2021. PMID: 34337554 Free PMC article.
Metabolomics reveals biotic and abiotic elicitor effects on the soft coral Sarcophyton ehrenbergi terpenoid content.
Farag MA, Al-Mahdy DA, Meyer A, Westphal H, Wessjohann LA. Farag MA, et al. Sci Rep. 2017 Apr 5;7(1):648. doi: 10.1038/s41598-017-00527-8. Sci Rep. 2017. PMID: 28381824 Free PMC article.
The effects of six biotic and abiotic elicitors, i.e. MeJA (methyl jasmonate), SA (salicylic acid), ZnCl(2), glutathione and beta-glucan BG (fungal elicitor), and wounding, on the secondary metabolite accumulation in the soft coral Sarcophyton ehrenbergi were assessed. ... …
The effects of six biotic and abiotic elicitors, i.e. MeJA (methyl jasmonate), SA (salicylic acid), ZnCl(2), glutathione and beta-glu …
Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study.
Farrag ARH, Abdallah HMI, Khattab AR, Elshamy AI, Gendy AEGE, Mohamed TA, Farag MA, Efferth T, Hegazy MF. Farrag ARH, et al. Phytomedicine. 2019 Sep;62:152970. doi: 10.1016/j.phymed.2019.152970. Epub 2019 May 30. Phytomedicine. 2019. PMID: 31181403
Ranitidine (50 mg/kg) was used as standard anti-ulcer drug. After 4 h, the ulcer number and the total ulcer score were determined and TNF-alpha was assessed. ...The metabolome heterogeneity of the different extracts was explored using (UPLC-MS) aided by supervised pattern …
Ranitidine (50 mg/kg) was used as standard anti-ulcer drug. After 4 h, the ulcer number and the total ulcer score were determined and …
Thrombosis, Bleeding, and the Observational Effect of Early Therapeutic Anticoagulation on Survival in Critically Ill Patients With COVID-19.
Al-Samkari H, Gupta S, Leaf RK, Wang W, Rosovsky RP, Brenner SK, Hayek SS, Berlin H, Kapoor R, Shaefi S, Melamed ML, Sutherland A, Radbel J, Green A, Garibaldi BT, Srivastava A, Leonberg-Yoo A, Shehata AM, Flythe JE, Rashidi A, Goyal N, Chan L, Mathews KS, Hedayati SS, Dy R, Toth-Manikowski SM, Zhang J, Mallappallil M, Redfern RE, Bansal AD, Short SAP, Vangel MG, Admon AJ, Semler MW, Bauer KA, Hernán MA, Leaf DE; STOP-COVID Investigators. Al-Samkari H, et al. Ann Intern Med. 2021 May;174(5):622-632. doi: 10.7326/M20-6739. Epub 2021 Jan 26. Ann Intern Med. 2021. PMID: 33493012 Free PMC article.
Metabolome based classification of artichoke leaf: A prospect for phyto-equivalency of its different leaf origins and commercial preparations.
Farag MA, Elsebai MF, Khattab AR. Farag MA, et al. J Pharm Biomed Anal. 2018 Sep 5;158:151-159. doi: 10.1016/j.jpba.2018.05.046. Epub 2018 May 30. J Pharm Biomed Anal. 2018. PMID: 29909318
PCA analysis of 3 commercial artichoke preparations showed discrimination of a silymarin-containing capsule suggesting that NMR can distinguish liver-aid herbal preparations based on its different chemical composition. Quantitative (1)H NMR (qHNMR) was further employed to …
PCA analysis of 3 commercial artichoke preparations showed discrimination of a silymarin-containing capsule suggesting that NMR can distingu …