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Antisense oligonucleotides: absorption, distribution, metabolism, and excretion.
Shadid M, Badawi M, Abulrob A. Shadid M, et al. Expert Opin Drug Metab Toxicol. 2021 Nov;17(11):1281-1292. doi: 10.1080/17425255.2021.1992382. Epub 2021 Oct 22. Expert Opin Drug Metab Toxicol. 2021. PMID: 34643122 Review.
EXPERT OPINION: Understanding the ADME properties of existing ASOs can foster further improvement of this cutting-edge therapy, thereby enabling researchers to safely develop ASO drugs and enhancing their ability to innovate. ABBREVIATIONS: 2'-MOE, 2'-O-methoxyethyl; 2'PS, …
EXPERT OPINION: Understanding the ADME properties of existing ASOs can foster further improvement of this cutting-edge therapy, thereby enab …
2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study.
AboulWafa OM, Daabees HMG, Badawi WA. AboulWafa OM, et al. Bioorg Chem. 2020 Jun;99:103798. doi: 10.1016/j.bioorg.2020.103798. Epub 2020 Mar 29. Bioorg Chem. 2020. PMID: 32247112 Review.
Binding interaction details for the most promising inhibitors with the active site of the target enzymes EGFR and ARO utilizing MOE-dock method are also reported....
Binding interaction details for the most promising inhibitors with the active site of the target enzymes EGFR and ARO utilizing MOE-d …
Influence of Moringa oleifera extract, vitamin C, and sodium bicarbonate on heat stress-induced HSP70 expression and cellular immune response in rabbits.
Abdel-Latif M, Sakran T, Badawi YK, Abdel-Hady DS. Abdel-Latif M, et al. Cell Stress Chaperones. 2018 Sep;23(5):975-984. doi: 10.1007/s12192-018-0906-1. Epub 2018 May 4. Cell Stress Chaperones. 2018. PMID: 29728855 Free PMC article.
The current study aimed to test the effect of Moringa oleifera extract (MOE), vitamin (Vit) C, and sodium bicarbonate (NaHCO(3)) on heat stress (HS)-induced alterations in rabbits. Five groups of rabbits were designed as control, HS, HS + MOE, HS + Vit C, and HS + N …
The current study aimed to test the effect of Moringa oleifera extract (MOE), vitamin (Vit) C, and sodium bicarbonate (NaHCO(3)) on h …