Cooperation of endogenous and exogenous reactive oxygen species induced by zinc peroxide nanoparticles to enhance oxidative stress-based cancer therapy.
Lin LS, Wang JF, Song J, Liu Y, Zhu G, Dai Y, Shen Z, Tian R, Song J, Wang Z, Tang W, Yu G, Zhou Z, Yang Z, Huang T, Niu G, Yang HH, Chen ZY, Chen X.
Lin LS, et al.
Theranostics. 2019 Sep 23;9(24):7200-7209. doi: 10.7150/thno.39831. eCollection 2019.
Theranostics. 2019.
PMID: 31695762
Free PMC article.
Methods: A ROS-generating agent based on polymer-modified zinc peroxide nanoparticles (ZnO(2) NPs) was presented, which simultaneously delivered exogenous H(2)O(2) and Zn(2+) capable of amplifying endogenous ROS production for synergistic cancer therapy. Results: After int …
Methods: A ROS-generating agent based on polymer-modified zinc peroxide nanoparticles (ZnO(2) NPs) was presented, which simultaneously deliv …