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The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation.
Cristóvão JS, Morris VK, Cardoso I, Leal SS, Martínez J, Botelho HM, Göbl C, David R, Kierdorf K, Alemi M, Madl T, Fritz G, Reif B, Gomes CM. Cristóvão JS, et al. Among authors: alemi m. Sci Adv. 2018 Jun 29;4(6):eaaq1702. doi: 10.1126/sciadv.aaq1702. eCollection 2018 Jun. Sci Adv. 2018. PMID: 29963623 Free PMC article.
Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
Rios X, Gómez-Vallejo V, Martín A, Cossío U, Morcillo MÁ, Alemi M, Cardoso I, Quintana J, Jiménez-Barbero J, Cotrina EY, Valencia G, Arsequell G, Llop J. Rios X, et al. Among authors: alemi m. Sci Rep. 2019 Sep 20;9(1):13672. doi: 10.1038/s41598-019-50071-w. Sci Rep. 2019. PMID: 31541162 Free PMC article.
Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
Gimeno A, Santos LM, Alemi M, Rivas J, Blasi D, Cotrina EY, Llop J, Valencia G, Cardoso I, Quintana J, Arsequell G, Jiménez-Barbero J. Gimeno A, et al. Among authors: alemi m. J Med Chem. 2017 Jul 13;60(13):5749-5758. doi: 10.1021/acs.jmedchem.7b00428. Epub 2017 Jun 16. J Med Chem. 2017. PMID: 28587455