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The peroxisome proliferator-activated receptor gamma (PPARγ) agonist, rosiglitazone, ameliorates neurofunctional and neuroinflammatory abnormalities in a rat model of Gulf War Illness.
Keledjian K, Tsymbalyuk O, Semick S, Moyer M, Negoita S, Kim K, Ivanova S, Gerzanich V, Simard JM. Keledjian K, et al. Among authors: moyer m. PLoS One. 2020 Nov 13;15(11):e0242427. doi: 10.1371/journal.pone.0242427. eCollection 2020. PLoS One. 2020. PMID: 33186383 Free PMC article.
Chronic neuronal activation leads to elevated lactate dehydrogenase A through the AMP-activated protein kinase/hypoxia-inducible factor-1α hypoxia pathway.
Ksendzovsky A, Bachani M, Altshuler M, Walbridge S, Mortazavi A, Moyer M, Chen C, Fayed I, Steiner J, Edwards N, Inati SK, Jahanipour J, Maric D, Heiss JD, Kapur J, Zaghloul KA. Ksendzovsky A, et al. Among authors: moyer m. Brain Commun. 2022 Dec 1;5(1):fcac298. doi: 10.1093/braincomms/fcac298. eCollection 2023. Brain Commun. 2022. PMID: 36655171 Free PMC article.