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Year Number of Results
1948 2
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1953 4
1954 2
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1956 3
1957 1
1959 1
1960 1
1964 6
1965 5
1966 7
1967 6
1968 6
1969 17
1970 11
1971 11
1972 14
1973 9
1974 7
1975 16
1976 22
1977 13
1978 13
1979 13
1980 11
1981 16
1982 23
1983 31
1984 33
1985 27
1986 27
1987 21
1988 34
1989 45
1990 31
1991 41
1992 46
1993 40
1994 54
1995 60
1996 57
1997 74
1998 72
1999 55
2000 73
2001 92
2002 81
2003 79
2004 81
2005 94
2006 133
2007 112
2008 126
2009 143
2010 145
2011 179
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2013 162
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2015 198
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4,973 results

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The following term was not found in PubMed: Ristiyani
Page 1
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation.
Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB. Zhong B, et al. Immunity. 2008 Oct 17;29(4):538-50. doi: 10.1016/j.immuni.2008.09.003. Epub 2008 Sep 25. Immunity. 2008. PMID: 18818105 Free article.
Overexpression of MITA activated IRF3, whereas knockdown of MITA inhibited virus-triggered activation of IRF3, expression of type I IFNs, and cellular antiviral response. ...MITA was phosphorylated by TBK1, which is required for MITA-mediated activatio …
Overexpression of MITA activated IRF3, whereas knockdown of MITA inhibited virus-triggered activation of IRF3, expression of t …
Mitochondrial DNA-triggered innate immune response: mechanisms and diseases.
Hu MM, Shu HB. Hu MM, et al. Cell Mol Immunol. 2023 Dec;20(12):1403-1412. doi: 10.1038/s41423-023-01086-x. Epub 2023 Nov 7. Cell Mol Immunol. 2023. PMID: 37932533 Free PMC article. Review.
Various cellular stress conditions trigger mitochondrial DNA (mtDNA) release from mitochondria into the cytosol. The released mtDNA is sensed by the cGAS-MITA/STING pathway, resulting in the induced expression of type I interferon and other effector genes. ...In this revie …
Various cellular stress conditions trigger mitochondrial DNA (mtDNA) release from mitochondria into the cytosol. The released mtDNA is sense …
MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention.
Zhong B, Shu HB. Zhong B, et al. Curr Opin Immunol. 2022 Oct;78:102248. doi: 10.1016/j.coi.2022.102248. Epub 2022 Sep 30. Curr Opin Immunol. 2022. PMID: 36193584 Review.
Here, we summarize the most recent progress on MITA-mediated signaling in a view of evolution and highlight the roles of MITA in human inflammatory disorders caused by gene mutations and in genetically modified mouse models. We also briefly introduce the chemicals t …
Here, we summarize the most recent progress on MITA-mediated signaling in a view of evolution and highlight the roles of MITA …
Mitotic inactivation of the cGAS-MITA/STING pathways.
Zhong L, Shu HB. Zhong L, et al. J Mol Cell Biol. 2021 Dec 30;13(10):721-727. doi: 10.1093/jmcb/mjab061. J Mol Cell Biol. 2021. PMID: 34609492 Free PMC article. Review.
How the cGAS-MITA/STING axis is inactivated upon nuclear envelope breakdown (NEBD) at mitotic entry in vertebrate cells to avoid self-DNA sensing remains unclear until very recently. In this review, we summarize the recent advances on how cGAS responds to chromosomes upon …
How the cGAS-MITA/STING axis is inactivated upon nuclear envelope breakdown (NEBD) at mitotic entry in vertebrate cells to avoid self …
Regulation and function of the cGAS-MITA/STING axis in health and disease.
Zhang ZD, Zhong B. Zhang ZD, et al. Cell Insight. 2022 Jan 5;1(1):100001. doi: 10.1016/j.cellin.2021.100001. eCollection 2022 Feb. Cell Insight. 2022. PMID: 37192983 Free PMC article. Review.
The cGAS-MITA/STING signaling critically mediates immune responses against DNA viruses, retroviruses, bacteria, and protozoan parasites. In addition, recent discoveries have extended our understanding of the roles of the cGAS-MITA/STING pathway in autoimmune disease …
The cGAS-MITA/STING signaling critically mediates immune responses against DNA viruses, retroviruses, bacteria, and protozoan parasit …
Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115.
Zhang ZD, Shi CR, Li FX, Gan H, Wei Y, Zhang Q, Shuai X, Chen M, Lin YL, Xiong TC, Chen X, Zhong B, Lin D. Zhang ZD, et al. Cell Mol Immunol. 2024 Mar;21(3):275-291. doi: 10.1038/s41423-024-01131-3. Epub 2024 Jan 24. Cell Mol Immunol. 2024. PMID: 38267694
STING (also known as MITA) is an adaptor protein that mediates cytoplasmic DNA-triggered signaling, and aberrant activation of STING/MITA by cytosolic self-DNA or gain-of-function mutations causes severe inflammation. ...
STING (also known as MITA) is an adaptor protein that mediates cytoplasmic DNA-triggered signaling, and aberrant activation of STING/ …
Furosemide.
[No authors listed] [No authors listed] 2022 May 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2022 May 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999869 Free Books & Documents. Review.
MITA Promotes Macrophage Proinflammatory Polarization and Its circRNA-Related Regulatory Mechanism in Recurrent Miscarriage.
Liu B, Liu J, Qiu Y, Chen J, Yang J. Liu B, et al. Int J Mol Sci. 2023 May 31;24(11):9545. doi: 10.3390/ijms24119545. Int J Mol Sci. 2023. PMID: 37298501 Free PMC article.
MITA (also called STING), a master regulator of DNA-mediated innate immune activation, is a potential therapeutic target for viral infection and virus-related diseases. ...In this study, we validated that the decidual M1/M2 ratio was upregulated in RM patients, suggesting …
MITA (also called STING), a master regulator of DNA-mediated innate immune activation, is a potential therapeutic target for viral in …
β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response.
Guo Y, Zhang XN, Su S, Ruan ZL, Hu MM, Shu HB. Guo Y, et al. Cell Mol Immunol. 2023 Feb;20(2):175-188. doi: 10.1038/s41423-022-00967-x. Epub 2023 Jan 5. Cell Mol Immunol. 2023. PMID: 36600052 Free PMC article.
Upon viral infection, cytoplasmic pattern recognition receptors detect viral nucleic acids and activate the adaptor protein VISA/MAVS- or MITA/STING-mediated innate antiviral response. Whether and how the innate antiviral response is regulated by neuronal endocrine functio …
Upon viral infection, cytoplasmic pattern recognition receptors detect viral nucleic acids and activate the adaptor protein VISA/MAVS- or …
Reply.
Sugisaki K, Inoue T, Yoshikawa K, Kanamori A, Yamazaki Y, Ishikawa S, Uchida K, Iwase A, Araie M. Sugisaki K, et al. Ophthalmology. 2022 Aug;129(8):e82-e83. doi: 10.1016/j.ophtha.2022.03.025. Epub 2022 May 20. Ophthalmology. 2022. PMID: 35599066 No abstract available.
4,973 results