Rational design of mitochondria targeted thiabendazole-based Ir(III) biscyclometalated complexes for a multimodal photodynamic therapy of cancer.
Echevarría I, Zafon E, Barrabés S, Martínez MÁ, Ramos-Gómez S, Ortega N, Manzano BR, Jalón FA, Quesada R, Espino G, Massaguer A.
Echevarría I, et al.
J Inorg Biochem. 2022 Jun;231:111790. doi: 10.1016/j.jinorgbio.2022.111790. Epub 2022 Mar 14.
J Inorg Biochem. 2022.
PMID: 35306449
Free article.
This work describes the synthesis of a family of Ir(III) complexes of general formula [Ir(C^N)(2)(N^N')]Cl (N^N' = thiabendazole-based ligands; C^N = ppy (2-phenylpyridinate) (Series A), or dfppy (2-(2,4-difluorophenyl)pyridinate) (Series B)) and their evaluation as potent …
This work describes the synthesis of a family of Ir(III) complexes of general formula [Ir(C^N)(2)(N^N')]Cl (N^N' = thiabendazole-based ligan …