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Page 1
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.
Jaworek T, Xu H, Gaynor BJ, Cole JW, Rannikmae K, Stanne TM, Tomppo L, Abedi V, Amouyel P, Armstrong ND, Attia J, Bell S, Benavente OR, Boncoraglio GB, Butterworth A; Cervical Artery Dissections and Ischemic Stroke Patients (CADSIP) Consortium; Carcel-Marquez J, Chen Z, Chong M, Cruchaga C, Cushman M, Danesh J, Debette S, Duggan DJ, Durda JP, Engstrom G, Enzinger C, Faul JD, Fecteau NS, Fernandez-Cadenas I, Gieger C, Giese AK, Grewal RP, Grittner U, Havulinna AS, Heitsch L, Hochberg MC, Holliday E, Hu J, Ilinca A; INVENT Consortium; Irvin MR, Jackson RD, Jacob MA, Rabionet R, Jimenez-Conde J, Johnson JA, Kamatani Y, Kardia SLR, Koido M, Kubo M, Lange L, Lee JM, Lemmens R, Levi CR, Li J, Li L, Lin K, Lopez H, Luke S, Maguire J, McArdle PF, McDonough CW, Meschia JF, Metso T, Müller-Nurasyid M, O'Connor TD, O'Donnell M, Peddareddygari LR, Pera J, Perry JA, Peters A, Putaala J, Ray D, Rexrode K, Ribases M, Rosand J, Rothwell PM, Rundek T, Ryan KA, Sacco RL, Salomaa V, Sanchez-Mora C, Schmidt R, Sharma P, Slowik A, Smith JA, Smith NL, Wassertheil-Smoller S, Söderholm M, Stine OC, Strbian D, Sudlow CLM, Tatlisumak T, Terao C, Thijs V, Torres-Aguila NP, Trégouët DA, Tuladhar AM, Veldink … See abstract for full author list ➔ Jaworek T, et al. Neurology. 2022 Oct 17;99(16):e1738-e1754. doi: 10.1212/WNL.0000000000201006. Neurology. 2022. PMID: 36240095 Free PMC article.
Effectiveness and safety of dupilumab in patients with chronic rhinosinusitis with nasal polyps and associated comorbidities: a multicentric prospective study in real life.
Nettis E, Brussino L, Patella V, Bonzano L, Detoraki A, Di Leo E, Sirufo MM, Caruso C, Lodi Rizzini F, Conte M, Yacoub MR, Triggiani M, Ridolo E, Macchia L, Rolla G, Brancaccio R, De Paulis A, Spadaro G, Di Bona D, D'Uggento AM, Ginaldi L, Gaeta F, Nucera E, Jaubashi K, Villalta D, Dagna L, Ciotta D, Pucciarini F, Bagnasco D, Celi G, Chieco Bianchi F, Cosmi L, Costantino MT, Crivellaro MA, D'Alò S, Del Biondo P, Del Giacco S, Di Gioacchino M, Di Pietro L, Favero E, Gangemi S, Guarnieri G, Heffler E, Leto Barone MS, Lombardo C, Losa F, Matucci A, Minciullo PL, Parronchi P, Passalacqua G, Pucci S, Rossi O, Salvati L, Schiappoli M, Senna G, Vianello A, Vultaggio A, Baoran Y, Incorvaia C, Canonica GW. Nettis E, et al. Clin Mol Allergy. 2022 May 19;20(1):6. doi: 10.1186/s12948-022-00171-2. Clin Mol Allergy. 2022. PMID: 35590407 Free PMC article.
Riociguat in patients with early diffuse cutaneous systemic sclerosis (RISE-SSc): open-label, long-term extension of a phase 2b, randomised, placebo-controlled trial.
Distler O, Allanore Y, Denton CP, Kuwana M, Matucci-Cerinic M, Pope JE, Atsumi T, Bečvář R, Czirják L, Hachulla E, Ishii T, Ishikawa O, Johnson SR, De Langhe E, Stagnaro C, Riccieri V, Schiopu E, Silver RM, Smith V, Steen V, Stevens W, Szücs G, Truchetet ME, Wosnitza M, Laapas K, Kramer F, Khanna D. Distler O, et al. Lancet Rheumatol. 2023 Nov;5(11):e660-e669. doi: 10.1016/S2665-9913(23)00238-2. Lancet Rheumatol. 2023. PMID: 38251533 Clinical Trial.
A long-term treatment with taurine prevents cardiac dysfunction in mdx mice.
Mele A, Mantuano P, De Bellis M, Rana F, Sanarica F, Conte E, Morgese MG, Bove M, Rolland JF, Capogrosso RF, Pierno S, Camerino GM, Trabace L, De Luca A. Mele A, et al. Transl Res. 2019 Feb;204:82-99. doi: 10.1016/j.trsl.2018.09.004. Epub 2018 Sep 28. Transl Res. 2019. PMID: 30347179
Bergamot (Citrus bergamia) leaf extract improves metabolic, antioxidant and anti-inflammatory activity in skeletal muscles in a metabolic syndrome experimental model.
Palacio TLN, Siqueira JS, de Paula BH, Rego RMP, Vieira TA, Baron G, Altomare A, Ferron AJT, Aldini G, Kano HT, Correa CR. Palacio TLN, et al. Int J Food Sci Nutr. 2023 Feb;74(1):64-71. doi: 10.1080/09637486.2022.2154328. Epub 2022 Dec 15. Int J Food Sci Nutr. 2023. PMID: 36519349
Evaluation included nutritional, metabolic and hormonal analyses, along with measurements of inflammatory status and oxidative stress in soleus and extensor digitorum longus (EDL) muscles. BLE showed positive metabolic effects, with a reduction of plasma triglycerides and …
Evaluation included nutritional, metabolic and hormonal analyses, along with measurements of inflammatory status and oxidative stress in sol …
Intact Short, Intermediate, and Long Skeletal Muscle Fibers Obtained by Enzymatic Dissociation of Six Hindlimb Muscles of Mice: Beyond Flexor Digitorum Brevis.
Petro JL, Milán AF, Arenas E, Valle L, Hernández V, Calderón JC. Petro JL, et al. J Vis Exp. 2023 Dec 1;(202). doi: 10.3791/65851. J Vis Exp. 2023. PMID: 38108405
FDB gave short (<1 mm), peroneus digiti quarti (PDQA) and peroneus longus (PL) gave intermediate (1-3 mm), while extensor digitorum longus (EDL), extensor hallucis longus (EHL), and soleus muscles released long (3-6 mm) fibers. ...
FDB gave short (<1 mm), peroneus digiti quarti (PDQA) and peroneus longus (PL) gave intermediate (1-3 mm), while extensor digitorum longu …
Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia.
Ferri A, Panariti A, Miserocchi G, Rocchetti M, Buoli Comani G, Rivolta I, Bishop DJ. Ferri A, et al. Eur J Appl Physiol. 2018 Aug;118(8):1641-1652. doi: 10.1007/s00421-018-3897-9. Epub 2018 May 31. Eur J Appl Physiol. 2018. PMID: 29855791
Mitochondrial respiration was determined in permeabilised muscle fibres from left and right ventricles, soleus and extensorum digitorum longus (EDL). Citrate synthase activity and the relative abundance of proteins associated with mitochondrial biogenesis were also analyse …
Mitochondrial respiration was determined in permeabilised muscle fibres from left and right ventricles, soleus and extensorum digitorum long …
Glycosaminoglycans treatment increases IGF-I muscle levels and counteracts motor neuron death: A novel nonanticoagulant action.
Losa M, Vergani L, Lesma E, Rossoni G, Di Giulio AM, Vercelli A, Torsello A, Muller EE, Gorio A. Losa M, et al. J Neurosci Res. 1999 Feb 15;55(4):496-505. doi: 10.1002/(SICI)1097-4547(19990215)55:4<496::AID-JNR9>3.0.CO;2-6. J Neurosci Res. 1999. PMID: 10723059
EDL muscle denervation-induced atrophy in saline-treated rats is progressive and reaches the greatest extent at 42 days after birth, which correlates with reduced EDL weight growth. ...The number of surviving EDL motor neurons is also increased to 43 +/- 4. T …
EDL muscle denervation-induced atrophy in saline-treated rats is progressive and reaches the greatest extent at 42 days after birth, …
Systemic administration of insulin-like growth factor decreases motor neuron cell death and promotes muscle reinnervation.
Vergani L, Di Giulio AM, Losa M, Rossoni G, Muller EE, Gorio A. Vergani L, et al. J Neurosci Res. 1998 Dec 15;54(6):840-7. doi: 10.1002/(SICI)1097-4547(19981215)54:6<840::AID-JNR12>3.0.CO;2-L. J Neurosci Res. 1998. PMID: 9856868
The effect on motoneuron survival was accompanied by improved muscle fibre morphometry and restoration of indirect EDL muscle isometric twitch tension, which was about 80 % of control values for both doses of IGF-I compared with 60% observed with saline treatment. Reinnerv …
The effect on motoneuron survival was accompanied by improved muscle fibre morphometry and restoration of indirect EDL muscle isometr …