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Page 1
Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF.
Cermakova K, Tao L, Dejmek M, Sala M, Montierth MD, Chan YS, Patel I, Chambers C, Loeza Cabrera M, Hoffman D, Parchem RJ, Wang W, Nencka R, Barbieri E, Hodges HC. Cermakova K, et al. Among authors: dejmek m. Nucleic Acids Res. 2024 Jan 11;52(1):4-21. doi: 10.1093/nar/gkad1081. Nucleic Acids Res. 2024. PMID: 37993417 Free PMC article.
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
Štefek M, Chalupská D, Chalupský K, Zgarbová M, Dvořáková A, Krafčíková P, Li ASM, Šála M, Dejmek M, Otava T, Chaloupecká E, Kozák J, Kozic J, Vedadi M, Weber J, Mertlíková-Kaiserová H, Nencka R. Štefek M, et al. Among authors: dejmek m. ACS Omega. 2023 Jul 21;8(30):27410-27418. doi: 10.1021/acsomega.3c02815. eCollection 2023 Aug 1. ACS Omega. 2023. PMID: 37546609 Free PMC article.
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential.
Dejmek M, Šála M, Brazdova A, Vanekova L, Smola M, Klíma M, Břehová P, Buděšínský M, Dračínský M, Procházková E, Zavřel M, Šimák O, Páv O, Boura E, Birkuš G, Nencka R. Dejmek M, et al. Structure. 2022 Aug 4;30(8):1146-1156.e11. doi: 10.1016/j.str.2022.05.012. Epub 2022 Jun 10. Structure. 2022. PMID: 35690061 Free article.
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping.
Břehová P, Řezníčková E, Škach K, Jorda R, Dejmek M, Vojáčková V, Šála M, Kovalová M, Dračínský M, Dolníková A, Strmeň T, Kinnertová M, Chalupský K, Dvořáková A, Gucký T, Mertlíková Kaiserová H, Klener P, Nencka R, Kryštof V. Břehová P, et al. Among authors: dejmek m. J Med Chem. 2023 Aug 24;66(16):11133-11157. doi: 10.1021/acs.jmedchem.3c00575. Epub 2023 Aug 3. J Med Chem. 2023. PMID: 37535845 Free PMC article.
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
Vavřina Z, Perlíková P, Milisavljević N, Chevrier F, Smola M, Smith J, Dejmek M, Havlíček V, Buděšínský M, Liboska R, Vaneková L, Brynda J, Boura E, Řezáčová P, Hocek M, Birkuš G. Vavřina Z, et al. Among authors: dejmek m. J Med Chem. 2022 Oct 27;65(20):14082-14103. doi: 10.1021/acs.jmedchem.2c01305. Epub 2022 Oct 6. J Med Chem. 2022. PMID: 36201304 Free PMC article.
37 results