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CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models.
Seif M, Kakoschke TK, Ebel F, Bellet MM, Trinks N, Renga G, Pariano M, Romani L, Tappe B, Espie D, Donnadieu E, Hünniger K, Häder A, Sauer M, Damotte D, Alifano M, White PL, Backx M, Nerreter T, Machwirth M, Kurzai O, Prommersberger S, Einsele H, Hudecek M, Löffler J. Seif M, et al. Sci Transl Med. 2022 Sep 28;14(664):eabh1209. doi: 10.1126/scitranslmed.abh1209. Epub 2022 Sep 28. Sci Transl Med. 2022. PMID: 36170447
M2 polarization enhances silica nanoparticle uptake by macrophages.
Hoppstädter J, Seif M, Dembek A, Cavelius C, Huwer H, Kraegeloh A, Kiemer AK. Hoppstädter J, et al. Among authors: seif m. Front Pharmacol. 2015 Mar 23;6:55. doi: 10.3389/fphar.2015.00055. eCollection 2015. Front Pharmacol. 2015. PMID: 25852557 Free PMC article.
The domestic pig as human-relevant large animal model to study adaptive antifungal immune responses against airborne Aspergillus fumigatus.
Schmidt S, Ebner F, Rosen K, Kniemeyer O, Brakhage AA, Löffler J, Seif M, Springer J, Schlosser J, Scharek-Tedin L, Scheffold A, Bacher P, Kühl AA, Rösler U, Hartmann S. Schmidt S, et al. Among authors: seif m. Eur J Immunol. 2020 Nov;50(11):1712-1728. doi: 10.1002/eji.201948524. Epub 2020 Jul 13. Eur J Immunol. 2020. PMID: 32558930 Free article.