Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.
Luciano M, Hagenaars SP, Davies G, Hill WD, Clarke TK, Shirali M, Harris SE, Marioni RE, Liewald DC, Fawns-Ritchie C, Adams MJ, Howard DM, Lewis CM, Gale CR, McIntosh AM, Deary IJ.
Luciano M, et al.
Nat Genet. 2018 Jan;50(1):6-11. doi: 10.1038/s41588-017-0013-8. Epub 2017 Dec 18.
Nat Genet. 2018.
PMID: 29255261
Free PMC article.
Genetic signals were enriched in neuronal genesis and differentiation pathways, and substantial genetic correlations were found between neuroticism and depressive symptoms (r (g) = 0.82, standard error (s.e.) = 0.03), major depressive disorder (MDD; r (g) = 0.69, s.e …
Genetic signals were enriched in neuronal genesis and differentiation pathways, and substantial genetic correlations were found between neur …