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Tetra-hydro-alstonine.
Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 7;69(Pt 9):o1389-90. doi: 10.1107/S1600536813021168. eCollection 2013.
Acta Crystallogr Sect E Struct Rep Online. 2013.
PMID: 24427031
Free PMC article.
In the title compound, C21H24N2O3 [systematic name: methyl (20alpha)-16,17-dide-hydro-19alpha-methyl-18-oxayohimban-16-carb-oxy-l-ate], the mol-ecule adopts an L-type conformation. The crystal packing is governed by one N-Hpi and one C-Hpi inter-actions. The crystal cohesi …
In the title compound, C21H24N2O3 [systematic name: methyl (20alpha)-16,17-dide-hydro-19alpha-methyl-18-oxayohimban-16-carb-oxy-l-ate], the …
Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons.
Raffo-Romero A, Arab T, Al-Amri IS, Le Marrec-Croq F, Van Camp C, Lemaire Q, Salzet M, Vizioli J, Sautiere PE, Lefebvre C.
Raffo-Romero A, et al.
Int J Mol Sci. 2018 Dec 19;19(12):4124. doi: 10.3390/ijms19124124.
Int J Mol Sci. 2018.
PMID: 30572617
Free PMC article.
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A conserved phenylalanine of motif IV in superfamily 2 helicases is required for cooperative, ATP-dependent binding of RNA substrates in DEAD-box proteins.
Banroques J, Cordin O, Doère M, Linder P, Tanner NK.
Banroques J, et al.
Mol Cell Biol. 2008 May;28(10):3359-71. doi: 10.1128/MCB.01555-07. Epub 2008 Mar 10.
Mol Cell Biol. 2008.
PMID: 18332124
Free PMC article.
For DEAD-box proteins, the phenylalanine also aligns a highly conserved arginine of motif VI through van der Waals and cation-pi interactions, thereby helping to maintain the network of interactions that exist between the different motifs involved in ATP and RNA binding... …
For DEAD-box proteins, the phenylalanine also aligns a highly conserved arginine of motif VI through van der Waals and cation-pi inte …
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