Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells.
Wankel B, Ouyang J, Guo X, Hadjiolova K, Miller J, Liao Y, Tham DK, Romih R, Andrade LR, Gumper I, Simon JP, Sachdeva R, Tolmachova T, Seabra MC, Fukuda M, Schaeren-Wiemers N, Hong WJ, Sabatini DD, Wu XR, Kong X, Kreibich G, Rindler MJ, Sun TT.
Wankel B, et al.
Mol Biol Cell. 2016 May 15;27(10):1621-34. doi: 10.1091/mbc.E15-04-0230. Epub 2016 Mar 23.
Mol Biol Cell. 2016.
PMID: 27009205
Free PMC article.
These data support a unifying model in which UP cargoes are targeted for apical insertion via sequential interactions with Rabs and their effectors, SNAREs and MAL, and in which K20 plays a key role in regulating vesicular trafficking....
These data support a unifying model in which UP cargoes are targeted for apical insertion via sequential interactions with Rabs and t …