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Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8.
Tzioras M, Daniels MJD, Davies C, Baxter P, King D, McKay S, Varga B, Popovic K, Hernandez M, Stevenson AJ, Barrington J, Drinkwater E, Borella J, Holloway RK, Tulloch J, Moss J, Latta C, Kandasamy J, Sokol D, Smith C, Miron VE, Káradóttir RT, Hardingham GE, Henstridge CM, Brennan PM, McColl BW, Spires-Jones TL. Tzioras M, et al. Among authors: daniels mjd. Cell Rep Med. 2023 Sep 19;4(9):101175. doi: 10.1016/j.xcrm.2023.101175. Epub 2023 Aug 30. Cell Rep Med. 2023. PMID: 37652017 Free PMC article.
Boron-Based Inhibitors of the NLRP3 Inflammasome.
Baldwin AG, Rivers-Auty J, Daniels MJD, White CS, Schwalbe CH, Schilling T, Hammadi H, Jaiyong P, Spencer NG, England H, Luheshi NM, Kadirvel M, Lawrence CB, Rothwell NJ, Harte MK, Bryce RA, Allan SM, Eder C, Freeman S, Brough D. Baldwin AG, et al. Among authors: daniels mjd. Cell Chem Biol. 2017 Nov 16;24(11):1321-1335.e5. doi: 10.1016/j.chembiol.2017.08.011. Epub 2017 Sep 21. Cell Chem Biol. 2017. PMID: 28943355 Free PMC article.
Redefining the ancestral origins of the interleukin-1 superfamily.
Rivers-Auty J, Daniels MJD, Colliver I, Robertson DL, Brough D. Rivers-Auty J, et al. Among authors: daniels mjd. Nat Commun. 2018 Mar 20;9(1):1156. doi: 10.1038/s41467-018-03362-1. Nat Commun. 2018. PMID: 29559685 Free PMC article.
Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation.
Rivers-Auty J, Tapia VS, White CS, Daniels MJD, Drinkall S, Kennedy PT, Spence HG, Yu S, Green JP, Hoyle C, Cook J, Bradley A, Mather AE, Peters R, Tzeng TC, Gordon MJ, Beattie JH, Brough D, Lawrence CB. Rivers-Auty J, et al. Among authors: daniels mjd. J Neurosci. 2021 Mar 31;41(13):3025-3038. doi: 10.1523/JNEUROSCI.1980-20.2020. Epub 2021 Feb 17. J Neurosci. 2021. PMID: 33597269 Free PMC article.
The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes.
Tapia VS, Daniels MJD, Palazón-Riquelme P, Dewhurst M, Luheshi NM, Rivers-Auty J, Green J, Redondo-Castro E, Kaldis P, Lopez-Castejon G, Brough D. Tapia VS, et al. Among authors: daniels mjd. J Biol Chem. 2019 May 24;294(21):8325-8335. doi: 10.1074/jbc.RA119.008009. Epub 2019 Apr 2. J Biol Chem. 2019. PMID: 30940725 Free PMC article.
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Daniels MJ, et al. Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504. Nat Commun. 2016. PMID: 27509875 Free PMC article.