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Showing results for michael iggs
Your search for Michael Inggs retrieved no results
Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents.
Bernardim B, Matos MJ, Ferhati X, Compañón I, Guerreiro A, Akkapeddi P, Burtoloso ACB, Jiménez-Osés G, Corzana F, Bernardes GJL. Bernardim B, et al. Nat Protoc. 2019 Jan;14(1):86-99. doi: 10.1038/s41596-018-0083-9. Nat Protoc. 2019. PMID: 30470819
In this protocol, we describe a strategy for the irreversible and selective modification of cysteine residues on antibodies, using functionalized carbonylacrylic reagents. This protocol is based on a thiol-Michael-type addition of native or engineered cysteine residues to …
In this protocol, we describe a strategy for the irreversible and selective modification of cysteine residues on antibodies, using functiona …
A Preliminary Report: The Hippocampus and Surrounding Temporal Cortex of Patients With Schizophrenia Have Impaired Blood-Brain Barrier.
Goldwaser EL, Swanson RL 2nd, Arroyo EJ, Venkataraman V, Kosciuk MC, Nagele RG, Hong LE, Acharya NK. Goldwaser EL, et al. Front Hum Neurosci. 2022 Mar 31;16:836980. doi: 10.3389/fnhum.2022.836980. eCollection 2022. Front Hum Neurosci. 2022. PMID: 35431844 Free PMC article.
In this preliminary study, we used immunohistochemistry and serum immunoglobulin G (IgG) antibodies to investigate the state of BBB function in formalin-fixed postmortem samples from the hippocampus and surrounding temporal cortex of patients with schizophrenia (n = 25) and contr …
In this preliminary study, we used immunohistochemistry and serum immunoglobulin G (IgG) antibodies to investigate the state of BBB function …
An autoantibody in narcolepsy disrupts colonic migrating motor complexes.
Jackson MW, Reed JH, Smith AJ, Gordon TP. Jackson MW, et al. J Neurosci. 2008 Dec 3;28(49):13303-9. doi: 10.1523/JNEUROSCI.4489-08.2008. J Neurosci. 2008. PMID: 19052222 Free PMC article.
The effect of immunoglobulins prepared for clinical intravenous treatment (IVIg) on autoantibody-mediated colonic disruption was also assessed. Narcoleptic IgGs markedly reduced the frequency of CMMCs or irreversibly abolished them. ...
The effect of immunoglobulins prepared for clinical intravenous treatment (IVIg) on autoantibody-mediated colonic disruption was also assess …
Magnetic nanocomposites: versatile tool for the combination of immunomagnetic separation with flow-based chemiluminescence immunochip for rapid biosensing of Staphylococcal enterotoxin B in milk.
Nistler A, Niessner R, Seidel M. Nistler A, et al. Anal Bioanal Chem. 2019 Jul;411(19):4951-4961. doi: 10.1007/s00216-019-01808-z. Epub 2019 Apr 15. Anal Bioanal Chem. 2019. PMID: 30982928
Therefore, iron oxide-shell silica-core magnetic nanocomposites were conjugated to biotinylated anti-SEB antibodies (MNC-IgGs). MNC-IgGs were applied successfully for (i) capturing SEB in milk samples by an affinity reaction, (ii) magnetophoretic collection on antib …
Therefore, iron oxide-shell silica-core magnetic nanocomposites were conjugated to biotinylated anti-SEB antibodies (MNC-IgGs). MNC- …
Development of tetravalent, bispecific CCR5 antibodies with antiviral activity against CCR5 monoclonal antibody-resistant HIV-1 strains.
Schanzer J, Jekle A, Nezu J, Lochner A, Croasdale R, Dioszegi M, Zhang J, Hoffmann E, Dormeyer W, Stracke J, Schäfer W, Ji C, Heilek G, Cammack N, Brandt M, Umana P, Brinkmann U. Schanzer J, et al. Antimicrob Agents Chemother. 2011 May;55(5):2369-78. doi: 10.1128/AAC.00215-10. Epub 2011 Feb 7. Antimicrob Agents Chemother. 2011. PMID: 21300827 Free PMC article.
The basic protein formats that we applied were derived from Morrison-type bispecific antibodies: whole IgGs to which we connected single-chain antibodies (scFvs) via (Gly4Ser)n sequences at either the C or N terminus of the light chain or heavy chain. ...
The basic protein formats that we applied were derived from Morrison-type bispecific antibodies: whole IgGs to which we connected sin …
TriFabs--Trivalent IgG-Shaped Bispecific Antibody Derivatives: Design, Generation, Characterization and Application for Targeted Payload Delivery.
Mayer K, Baumann AL, Grote M, Seeber S, Kettenberger H, Breuer S, Killian T, Schäfer W, Brinkmann U. Mayer K, et al. Int J Mol Sci. 2015 Nov 17;16(11):27497-507. doi: 10.3390/ijms161126037. Int J Mol Sci. 2015. PMID: 26593903 Free PMC article.
TriFabs which bind one antigen bivalent in the same manner as IgGs and the second antigen monovalent "in between" these Fabs can be applied to simultaneously engage two antigens, or for targeted delivery of small and large (fluorescent or cytotoxic) payloads....
TriFabs which bind one antigen bivalent in the same manner as IgGs and the second antigen monovalent "in between" these Fabs can be a …
Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion.
Alam SM, Liao HX, Tomaras GD, Bonsignori M, Tsao CY, Hwang KK, Chen H, Lloyd KE, Bowman C, Sutherland L, Jeffries TL Jr, Kozink DM, Stewart S, Anasti K, Jaeger FH, Parks R, Yates NL, Overman RG, Sinangil F, Berman PW, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Karasavva N, Rerks-Ngarm S, Kim JH, Michael NL, Zolla-Pazner S, Santra S, Letvin NL, Harrison SC, Haynes BF. Alam SM, et al. J Virol. 2013 Feb;87(3):1554-68. doi: 10.1128/JVI.00718-12. Epub 2012 Nov 21. J Virol. 2013. PMID: 23175357 Free PMC article.
Analysis of A244 gp120, with or without delta11 or gD, demonstrated that the delta11 deletion, without the addition of gD, was sufficient for enhanced antigenicity to gp120 C1 region, conformational V2, and V1/V2 gp120 conformational epitopes. RV144 vaccinee serum IgGs bou …
Analysis of A244 gp120, with or without delta11 or gD, demonstrated that the delta11 deletion, without the addition of gD, was sufficient fo …
Antibody responses to P. falciparum blood stage antigens and incidence of clinical malaria in children living in endemic area in Burkina Faso.
Cherif MK, Ouédraogo O, Sanou GS, Diarra A, Ouédraogo A, Tiono A, Cavanagh DR, Michael T, Konaté AT, Watson NL, Sanza M, Dube TJT, Sirima SB, Nebié I. Cherif MK, et al. BMC Res Notes. 2017 Sep 8;10(1):472. doi: 10.1186/s13104-017-2772-9. BMC Res Notes. 2017. PMID: 28886727 Free PMC article.
All IgG subclasses were associated with low incidence of P. falciparum malaria, but these associations were stronger for cytophilic IgGs. CONCLUSIONS: On the basis of the data presented in this study, we conclude that the induction of humoral immune response to tested mala …
All IgG subclasses were associated with low incidence of P. falciparum malaria, but these associations were stronger for cytophilic IgGs …