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Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma.
Shirinbak S, Chan RY, Shahani S, Muthugounder S, Kennedy R, Hung LT, Fernandez GE, Hadjidaniel MD, Moghimi B, Sheard MA, Epstein AL, Fabbri M, Shimada H, Asgharzadeh S. Shirinbak S, et al. Among authors: hadjidaniel md. Oncoimmunology. 2021 Jan 4;10(1):1838140. doi: 10.1080/2162402X.2020.1838140. Oncoimmunology. 2021. PMID: 33489468 Free PMC article.
Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma.
Asgharzadeh S, Salo JA, Ji L, Oberthuer A, Fischer M, Berthold F, Hadjidaniel M, Liu CW, Metelitsa LS, Pique-Regi R, Wakamatsu P, Villablanca JG, Kreissman SG, Matthay KK, Shimada H, London WB, Sposto R, Seeger RC. Asgharzadeh S, et al. Among authors: hadjidaniel m. J Clin Oncol. 2012 Oct 1;30(28):3525-32. doi: 10.1200/JCO.2011.40.9169. Epub 2012 Aug 27. J Clin Oncol. 2012. PMID: 22927533 Free PMC article.
Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC.
Hadjidaniel MD, Muthugounder S, Hung LT, Sheard MA, Shirinbak S, Chan RY, Nakata R, Borriello L, Malvar J, Kennedy RJ, Iwakura H, Akamizu T, Sposto R, Shimada H, DeClerck YA, Asgharzadeh S. Hadjidaniel MD, et al. Oncotarget. 2017 Sep 16;8(53):91516-91529. doi: 10.18632/oncotarget.21066. eCollection 2017 Oct 31. Oncotarget. 2017. PMID: 29207662 Free PMC article.
Exosome-mediated transfer of microRNAs within the tumor microenvironment and neuroblastoma resistance to chemotherapy.
Challagundla KB, Wise PM, Neviani P, Chava H, Murtadha M, Xu T, Kennedy R, Ivan C, Zhang X, Vannini I, Fanini F, Amadori D, Calin GA, Hadjidaniel M, Shimada H, Jong A, Seeger RC, Asgharzadeh S, Goldkorn A, Fabbri M. Challagundla KB, et al. Among authors: hadjidaniel m. J Natl Cancer Inst. 2015 May 13;107(7):djv135. doi: 10.1093/jnci/djv135. Print 2015 Jul. J Natl Cancer Inst. 2015. PMID: 25972604 Free PMC article.
MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT.
Keravnou A, Ioannides M, Loizides C, Tsangaras K, Achilleos A, Mina P, Kypri E, Hadjidaniel MD, Neofytou M, Kyriacou S, Sismani C, Koumbaris G, Patsalis PC. Keravnou A, et al. Among authors: hadjidaniel md. PLoS One. 2018 Jun 11;13(6):e0199010. doi: 10.1371/journal.pone.0199010. eCollection 2018. PLoS One. 2018. PMID: 29889893 Free PMC article.
Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.
Keravnou A, Ioannides M, Tsangaras K, Loizides C, Hadjidaniel MD, Papageorgiou EA, Kyriakou S, Antoniou P, Mina P, Achilleos A, Neofytou M, Kypri E, Sismani C, Koumbaris G, Patsalis PC. Keravnou A, et al. Among authors: hadjidaniel md. Genet Res (Camb). 2016 Nov 11;98:e15. doi: 10.1017/S0016672316000136. Genet Res (Camb). 2016. PMID: 27834155 Free PMC article.
Bisulfite Conversion of DNA: Performance Comparison of Different Kits and Methylation Quantitation of Epigenetic Biomarkers that Have the Potential to Be Used in Non-Invasive Prenatal Testing.
Leontiou CA, Hadjidaniel MD, Mina P, Antoniou P, Ioannides M, Patsalis PC. Leontiou CA, et al. Among authors: hadjidaniel md. PLoS One. 2015 Aug 6;10(8):e0135058. doi: 10.1371/journal.pone.0135058. eCollection 2015. PLoS One. 2015. PMID: 26247357 Free PMC article.