Michael D. Barker - Search Results

Year	Number of Results
2002	2
2003	3
2004	1
2005	3
2007	1
2009	2
2010	2
2011	1
2012	1
2013	1
2014	1
2015	1
2016	3
2018	1
2020	2
2021	2
2022	1
2023	2
2024	0

1

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, Lind KE, Locke K, Maller C, Martinod K, Patten C, Polyakova O, Rise CE, Rüdiger M, Sheppard RJ, Slade DJ, Thomas P, Thorpe J, Yao G, Drewes G, Wagner DD, Thompson PR, Prinjha RK, Wilson DM. Lewis HD, et al. Among authors: barker md. Nat Chem Biol. 2015 Mar;11(3):189-91. doi: 10.1038/nchembio.1735. Epub 2015 Jan 26. Nat Chem Biol. 2015. PMID: 25622091 Free PMC article.

2

Covalent targeting of non-cysteine residues in PI4KIIIβ.

Cosgrove B, Grant EK, Bertrand S, Down KD, Somers DO, P Evans J, Tomkinson NCO, Barker MD. Cosgrove B, et al. Among authors: barker md. RSC Chem Biol. 2023 Oct 17;4(12):1111-1122. doi: 10.1039/d3cb00142c. eCollection 2023 Nov 29. RSC Chem Biol. 2023. PMID: 38033723 Free PMC article.

3

TIMP3 mutation in Sorsby's fundus dystrophy: molecular insights.

Li Z, Clarke MP, Barker MD, McKie N. Li Z, et al. Among authors: barker md. Expert Rev Mol Med. 2005 Oct 31;7(24):1-15. doi: 10.1017/S1462399405010045. Expert Rev Mol Med. 2005. PMID: 16259644 Review.

4

Evidence that all Sorsby's fundus dystrophy mutations cause TIMP3 dimerization resulting in impaired inhibition of VEGFR2.

Alsaffar FA, Mujamammi AH, Aldughaim MSK, Nicklin MJH, Barker MD. Alsaffar FA, et al. Among authors: barker md. Genes Dis. 2022 Apr 12;10(1):45-47. doi: 10.1016/j.gendis.2022.03.008. eCollection 2023 Jan. Genes Dis. 2022. PMID: 37013036 Free PMC article. No abstract available.

5

Investigating the effects of the core nitrogen atom configuration on the thermodynamic solubility of 6,5-bicyclic heterocycles.

Cosgrove B, Down K, Bertrand S, Tomkinson NCO, Barker MD. Cosgrove B, et al. Among authors: barker md. Bioorg Med Chem Lett. 2021 Feb 1;33:127752. doi: 10.1016/j.bmcl.2020.127752. Epub 2020 Dec 29. Bioorg Med Chem Lett. 2021. PMID: 33359169 Free article.

6

Coupling of a Novel TIMP3 Peptide to Carboxypeptidase G2 for Pro-Drug Activation at the Tumour Site.

Aldughaim MS, Alsaffar F, Barker MD. Aldughaim MS, et al. Among authors: barker md. Molecules. 2021 Jan 25;26(3):625. doi: 10.3390/molecules26030625. Molecules. 2021. PMID: 33504102 Free PMC article.

7

Specific Targeting of PEGylated Liposomal Doxorubicin (Doxil^®) to Tumour Cells Using a Novel TIMP3 Peptide.

Aldughaim MS, Muthana M, Alsaffar F, Barker MD. Aldughaim MS, et al. Among authors: barker md. Molecules. 2020 Dec 28;26(1):100. doi: 10.3390/molecules26010100. Molecules. 2020. PMID: 33379361 Free PMC article.

8

Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease.

Barker MD, Liddle J, Atkinson FL, Wilson DM, Dickson MC, Ramirez-Molina C, Lewis H, Davis RP, Somers DO, Neu M, Jones E, Watson R. Barker MD, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3458-3462. doi: 10.1016/j.bmcl.2018.09.022. Epub 2018 Sep 18. Bioorg Med Chem Lett. 2018. PMID: 30249354

9

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.

Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Drewes G, Eagle R, Garton N, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, Katso R, Kruidenier L, Leveridge M, Pemberton M, Rioja I, Seal GA, Shipley T, Singh O, Suckling CJ, Taylor J, Thomas P, Wilson DM, Lee K, Prinjha RK. Westaway SM, et al. Among authors: barker md. J Med Chem. 2016 Feb 25;59(4):1370-87. doi: 10.1021/acs.jmedchem.5b01538. Epub 2016 Jan 15. J Med Chem. 2016. PMID: 26771203

10

Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture.

Coughlan TC, Crawford A, Goldring MB, Hatton PV, Barker MD. Coughlan TC, et al. Among authors: barker md. J Tissue Eng Regen Med. 2010 Dec;4(8):611-8. doi: 10.1002/term.275. J Tissue Eng Regen Med. 2010. PMID: 20568084 Free PMC article.

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