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An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo.
Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zentner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Baliban SM, et al. Among authors: michael a. Infect Immun. 2014 Oct;82(10):4080-91. doi: 10.1128/IAI.01950-14. Epub 2014 Jul 14. Infect Immun. 2014. PMID: 25024365 Free PMC article.
These data demonstrate the robust immunogenicity and efficacy of a TcdA/B RBD-based DNA vaccine in preclinical models of acute toxin-associated and intragastric, spore-induced colonic disease....
These data demonstrate the robust immunogenicity and efficacy of a TcdA/B RBD-based DNA vaccine in preclinical models of acute toxin-associa …
Schistosoma haematobium infection in the white mouse--histopathological and histochemical studies.
Farag HF, Awadalla HN, Girgis RS, Michael AI. Farag HF, et al. Among authors: michael ai. Angew Parasitol. 1980 Feb;21(1):20-6. Angew Parasitol. 1980. PMID: 7377626
Pathological changes during early prepatency matched with those in S. mansoni infection. Eggs were laid in aggregates in the colon and liver. They initiated the development of typical granulomatous lesions. ...
Pathological changes during early prepatency matched with those in S. mansoni infection. Eggs were laid in aggregates in the colon an …