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Showing results for mendelian lv
Search for Menglian Lv instead (3 results)
Insights into modifiable risk factors of cholelithiasis: A Mendelian randomization study.
Chen L, Yang H, Li H, He C, Yang L, Lv G. Chen L, et al. Hepatology. 2022 Apr;75(4):785-796. doi: 10.1002/hep.32183. Epub 2021 Dec 13. Hepatology. 2022. PMID: 34624136 Free PMC article.
Summary-level statistical data for cholelithiasis were obtained from FinnGen and UK Biobank (UKB) consortia. Both univariable and multivariable Mendelian randomization (MR) analyses were conducted to identify causal risk factors of cholelithiasis. ...
Summary-level statistical data for cholelithiasis were obtained from FinnGen and UK Biobank (UKB) consortia. Both univariable and multivaria …
Genetically predicted levels of folate, vitamin B(12), and risk of autoimmune diseases: A Mendelian randomization study.
Yang H, Song J, Li A, Lv L, Sun X, Mao Y, Ye D. Yang H, et al. Front Immunol. 2023 Mar 10;14:1139799. doi: 10.3389/fimmu.2023.1139799. eCollection 2023. Front Immunol. 2023. PMID: 36969181 Free PMC article.
OBJECTIVE: We aimed to investigate the relationship of folate and vitamin B(12) with autoimmune diseases using Mendelian randomization (MR). MATERIALS AND METHODS: We selected single-nucleotide polymorphisms associated with folate and vitamin B(12) at the genome-wide signi …
OBJECTIVE: We aimed to investigate the relationship of folate and vitamin B(12) with autoimmune diseases using Mendelian randomizatio …
Associations of cholecystectomy with the risk of colorectal cancer: a Mendelian randomization study.
Chen L, Fan Z, Sun X, Qiu W, Mu W, Chai K, Cao Y, Wang G, Lv G. Chen L, et al. Chin Med J (Engl). 2023 Apr 5;136(7):840-847. doi: 10.1097/CM9.0000000000002612. Chin Med J (Engl). 2023. PMID: 37027252 Free PMC article.
METHODS: We obtained genetic variants associated with cholecystectomy at a genome-wide significant level ( P value <5 10 -8 ) as instrumental variables (IVs) and performed Mendelian randomization (MR) to identify the complications of cholecystectomy. ...The study was re …
METHODS: We obtained genetic variants associated with cholecystectomy at a genome-wide significant level ( P value <5 10 -8 ) as instrume …
Periodontitis and stroke: A Mendelian randomization study.
Ma C, Wu M, Gao J, Liu C, Xie Y, Lv Q, Zhang X. Ma C, et al. Brain Behav. 2023 Feb;13(2):e2888. doi: 10.1002/brb3.2888. Epub 2023 Jan 9. Brain Behav. 2023. PMID: 36621868 Free PMC article.
We aimed to investigate the causal relationship of chronic periodontitis (CP) and aggressive periodontitis (AgP) with ischemic stroke and its subtypes in the Mendelian randomization framework. METHODS: The genetic proxies of CP were derived from large-scale summary statist …
We aimed to investigate the causal relationship of chronic periodontitis (CP) and aggressive periodontitis (AgP) with ischemic stroke and it …
Immune-mediated inflammatory diseases and risk of venous thromboembolism: A Mendelian randomization study.
Lv X, Gao X, Liu J, Deng Y, Nie Q, Fan X, Ye Z, Liu P, Wen J. Lv X, et al. Front Immunol. 2022 Dec 13;13:1042751. doi: 10.3389/fimmu.2022.1042751. eCollection 2022. Front Immunol. 2022. PMID: 36582224 Free PMC article.
However, a direct causally relation between IMIDs and VTE remains unclear to date. Here, we used Mendelian randomization (MR) analysis to investigate causal associations between IMIDs and VTE. ...
However, a direct causally relation between IMIDs and VTE remains unclear to date. Here, we used Mendelian randomization (MR) analysi …
The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study.
Reynolds CJ, Del Greco M F, Allen RJ, Flores C, Jenkins RG, Maher TM, Molyneaux PL, Noth I, Oldham JM, Wain LV, An J, Ong JS, MacGregor S, Yates TA, Cullinan P, Minelli C. Reynolds CJ, et al. Eur Respir J. 2023 May 25;61(5):2201585. doi: 10.1183/13993003.01585-2022. Print 2023 May. Eur Respir J. 2023. PMID: 37080571 Free PMC article.
It is not known if this association arises because GORD causes IPF or because IPF causes GORD, or because of confounding by factors, such as smoking, associated with both GORD and IPF. We used bidirectional Mendelian randomisation (MR), where genetic variants are used as i …
It is not known if this association arises because GORD causes IPF or because IPF causes GORD, or because of confounding by factors, such as …
Diet-derived antioxidants and nonalcoholic fatty liver disease: a Mendelian randomization study.
Chen L, Fan Z, Sun X, Qiu W, Mu W, Chai K, Cao Y, Wang G, Lv G. Chen L, et al. Hepatol Int. 2023 Apr;17(2):326-338. doi: 10.1007/s12072-022-10443-3. Epub 2022 Nov 10. Hepatol Int. 2023. PMID: 36352064
Genetic variants closely associated with the diet-derived antioxidants were selected to predict their circulating levels. A bi-directional Mendelian randomization (MR) design was employed to assess their causations. ...
Genetic variants closely associated with the diet-derived antioxidants were selected to predict their circulating levels. A bi-directional …
Causal relationship between obesity and iron deficiency anemia: a two-sample Mendelian randomization study.
Wang T, Gao Q, Yao Y, Luo G, Lv T, Xu G, Liu M, Xu J, Li X, Sun D, Cheng Z, Wang Y, Wu C, Wang R, Zou J, Yan M. Wang T, et al. Front Public Health. 2023 Jun 16;11:1188246. doi: 10.3389/fpubh.2023.1188246. eCollection 2023. Front Public Health. 2023. PMID: 37397759 Free PMC article.
Heterogeneity in the data was assessed using inverse variance-weighted regression, Mendelian randomization Egger regression, and Cochran's Q statistic. ...Outlier SNPs were identified using Mendelian randomization PRESSO analysis and "leave-one-out" analysis. ...
Heterogeneity in the data was assessed using inverse variance-weighted regression, Mendelian randomization Egger regression, and Coch …
Proteome-wide Mendelian randomization reveals the causal effects of immune-related plasma proteins on psychiatric disorders.
Dang X, Song M, Lv L, Yang Y, Luo XJ. Dang X, et al. Hum Genet. 2023 Jun;142(6):809-818. doi: 10.1007/s00439-023-02562-0. Epub 2023 Apr 21. Hum Genet. 2023. PMID: 37085628
Immune dysregulation has been consistently reported in psychiatric disorders, however, the causes and mechanisms underlying immune dysregulation in psychiatric disorders remain largely unclear. Here we conduct a Mendelian randomization study by integrating plasma proteome …
Immune dysregulation has been consistently reported in psychiatric disorders, however, the causes and mechanisms underlying immune dysregula …
Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study.
Deng Y, Li Q, Zhou F, Li G, Liu J, Lv J, Li L, Chang D. Deng Y, et al. Front Cardiovasc Med. 2022 Oct 24;9:1012615. doi: 10.3389/fcvm.2022.1012615. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36352846 Free PMC article.
This study aimed to investigate the associations between TL and CVDs using Mendelian randomization (MR). MATERIALS AND METHODS: In this two-sample MR study, we identified 154 independent TL-associated genetic variants from a genome-wide association study (GWAS) consisting …
This study aimed to investigate the associations between TL and CVDs using Mendelian randomization (MR). MATERIALS AND METHODS: In th …
227 results