The life and origin of medical learning from family of Yu Jinghe, renowned doctor of the Qing Dynasty, are described here in the form of chronicle. He was born in Yixing, Jiangsu. His parent died when he was a boy and he joined the Taiping Army for 5 years with difficult experiences. Later, he moved to Menghe and learned pharmacology from his elder brother. His works include Yu's Annotation on Shanghanlun Yi, Collection of Case Records on External Diseases, Collection After Practising Hour etc. Moreover, Yu's descendents and his close relationship with other modern celebrated doctors such as Ding Ganren and his son Ding Zhongying, and Yun Tieqiao are also mentioned.