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Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats.
Biomed Pharmacother. 2023 Dec;168:115803. doi: 10.1016/j.biopha.2023.115803. Epub 2023 Nov 3.
Biomed Pharmacother. 2023.
PMID: 37924790
Free article.
May 1,2-Dithiolane-4-carboxylic Acid and Its Derivatives Serve as a Specific Thioredoxin Reductase 1 Inhibitor?
Nikitjuka A, Krims-Davis K, Kaņepe-Lapsa I, Ozola M, Žalubovskis R.
Nikitjuka A, et al. Among authors: ozola m.
Molecules. 2023 Sep 15;28(18):6647. doi: 10.3390/molecules28186647.
Molecules. 2023.
PMID: 37764424
Free PMC article.
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Design, Synthesis, and Bioactivity Evaluations of 3-Methylenechroman-2-one Derivatives as Thioredoxin Reductase (TrxR) Inhibitors.
Nikitjuka A, Ozola M, Krims-Davis K, Žalubovskis R.
Nikitjuka A, et al. Among authors: ozola m.
ChemMedChem. 2024 Feb 1;19(3):e202300504. doi: 10.1002/cmdc.202300504. Epub 2023 Dec 13.
ChemMedChem. 2024.
PMID: 38063319
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Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver.
Liepinsh E, Zvejniece L, Clemensson L, Ozola M, Vavers E, Cirule H, Korzh S, Skuja S, Groma V, Briviba M, Grinberga S, Liu W, Olszewski P, Gentreau M, Fredriksson R, Dambrova M, Schiöth HB.
Liepinsh E, et al. Among authors: ozola m.
Br J Pharmacol. 2024 Apr 19. doi: 10.1111/bph.16363. Online ahead of print.
Br J Pharmacol. 2024.
PMID: 38641905
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