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A clinically relevant polymorphism in the Na+/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position.
J Biol Chem. 2021 Jan-Jun;296:100047. doi: 10.1074/jbc.RA120.014889. Epub 2020 Dec 2.
J Biol Chem. 2021.
PMID: 33168628
Free PMC article.
Structural Plasticity Is a Feature of Rheostat Positions in the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP).
Ruggiero MJ, Malhotra S, Fenton AW, Swint-Kruse L, Karanicolas J, Hagenbuch B.
Ruggiero MJ, et al.
Int J Mol Sci. 2022 Mar 16;23(6):3211. doi: 10.3390/ijms23063211.
Int J Mol Sci. 2022.
PMID: 35328632
Free PMC article.
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Perfluoroalkyl Carboxylic Acids Interact with the Human Bile Acid Transporter NTCP.
Ruggiero MJ, Miller H, Idowu JY, Zitzow JD, Chang SC, Hagenbuch B.
Ruggiero MJ, et al.
Livers. 2021 Dec;1(4):221-229. doi: 10.3390/livers1040017. Epub 2021 Oct 18.
Livers. 2021.
PMID: 34738093
Free PMC article.
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