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Modulation of riboflavin biosynthesis and utilization in mycobacteria.
Chengalroyen MD, Mehaffy C, Lucas M, Bauer N, Raphela ML, Oketade N, Warner DF, Lewinsohn DA, Lewinsohn DM, Dobos KM, Mizrahi V. Chengalroyen MD, et al. bioRxiv [Preprint]. 2023 Sep 10:2023.08.30.555301. doi: 10.1101/2023.08.30.555301. bioRxiv. 2023. PMID: 37693561 Free PMC article. Preprint.
DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis.
Chengalroyen MD, Mason MK, Borsellini A, Tassoni R, Abrahams GL, Lynch S, Ahn YM, Ambler J, Young K, Crowley BM, Olsen DB, Warner DF, Barry Iii CE, Boshoff HIM, Lamers MH, Mizrahi V. Chengalroyen MD, et al. ACS Infect Dis. 2022 Mar 11;8(3):612-625. doi: 10.1021/acsinfecdis.1c00643. Epub 2022 Feb 10. ACS Infect Dis. 2022. PMID: 35143160 Free PMC article.
Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs With Activity Against Mycobacterium tuberculosis.
Chengalroyen MD, Jordaan A, Seldon R, Ioerger T, Franzblau SG, Nasr M, Warner DF, Mizrahi V. Chengalroyen MD, et al. Front Cell Infect Microbiol. 2020 Nov 13;10:582416. doi: 10.3389/fcimb.2020.582416. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33282750 Free PMC article.