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Year Number of Results
2018 3
2019 3
2020 3
2021 3
2022 3
2023 1
2024 0

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15 results

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Page 1
Reprogramming of glucocorticoid receptor function by hypoxia.
Vanderhaeghen T, Timmermans S, Watts D, Paakinaho V, Eggermont M, Vandewalle J, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Dewaele S, Vanden Berghe J, Lemeire K, De Backer J, Dirkx L, Vanden Berghe W, Caljon G, Ghesquière B, De Bosscher K, Wielockx B, Palvimo JJ, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: eggermont m. EMBO Rep. 2022 Jan 5;23(1):e53083. doi: 10.15252/embr.202153083. Epub 2021 Oct 26. EMBO Rep. 2022. PMID: 34699114 Free PMC article.
The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function.
Vanderhaeghen T, Timmermans S, Eggermont M, Watts D, Vandewalle J, Wallaeys C, Nuyttens L, De Temmerman J, Hochepied T, Dewaele S, Berghe JV, Sanders N, Wielockx B, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: eggermont m. Front Immunol. 2023 Mar 16;14:1124011. doi: 10.3389/fimmu.2023.1124011. eCollection 2023. Front Immunol. 2023. PMID: 37006237 Free PMC article.
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding.
Timmermans S, Verhoog NJD, Van Looveren K, Dewaele S, Hochepied T, Eggermont M, Gilbert B, Boerema-de Munck A, Vanderhaeghen T, Vanden Berghe J, Garcia Gonzalez N, Vandewalle J, Bloch Y, Provost M, Savvides SN, De Bosscher K, Declercq W, Rottier RJ, Louw A, Libert C. Timmermans S, et al. Among authors: eggermont m. J Biol Chem. 2022 Feb;298(2):101574. doi: 10.1016/j.jbc.2022.101574. Epub 2022 Jan 8. J Biol Chem. 2022. PMID: 35007536 Free PMC article.
Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis.
Vandewalle J, Timmermans S, Paakinaho V, Vancraeynest L, Dewyse L, Vanderhaeghen T, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Eggermont M, Dewaele S, Velho TR, Moita LF, Weis S, Sponholz C, van Grunsven LA, Dewerchin M, Carmeliet P, De Bosscher K, Van de Voorde J, Palvimo JJ, Libert C. Vandewalle J, et al. Among authors: eggermont m. Cell Metab. 2021 Sep 7;33(9):1763-1776.e5. doi: 10.1016/j.cmet.2021.07.002. Epub 2021 Jul 23. Cell Metab. 2021. PMID: 34302744 Free article.
Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis.
Ballegeer M, Vandewalle J, Eggermont M, Van Isterdael G, Dejager L, De Bus L, Decruyenaere J, Vandenbroucke RE, Libert C. Ballegeer M, et al. Among authors: eggermont m. Shock. 2019 Aug;52(2):208-214. doi: 10.1097/SHK.0000000000001252. Shock. 2019. PMID: 30124596
ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation.
Van Wyngene L, Vanderhaeghen T, Petta I, Timmermans S, Corbeels K, Van der Schueren B, Vandewalle J, Van Looveren K, Wallaeys C, Eggermont M, Dewaele S, Catrysse L, van Loo G, Beyaert R, Vangoitsenhoven R, Nakayama T, Tavernier J, De Bosscher K, Libert C. Van Wyngene L, et al. Among authors: eggermont m. iScience. 2021 Jun 28;24(7):102790. doi: 10.1016/j.isci.2021.102790. eCollection 2021 Jul 23. iScience. 2021. PMID: 34337361 Free PMC article.
Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis.
Van Wyngene L, Vanderhaeghen T, Timmermans S, Vandewalle J, Van Looveren K, Souffriau J, Wallaeys C, Eggermont M, Ernst S, Van Hamme E, Gonçalves A, Eelen G, Remmerie A, Scott CL, Rombouts C, Vanhaecke L, De Bus L, Decruyenaere J, Carmeliet P, Libert C. Van Wyngene L, et al. Among authors: eggermont m. EMBO Mol Med. 2020 Feb 7;12(2):e11319. doi: 10.15252/emmm.201911319. Epub 2020 Jan 9. EMBO Mol Med. 2020. PMID: 31916705 Free PMC article.
Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium.
Souffriau J, Timmermans S, Vanderhaeghen T, Wallaeys C, Van Looveren K, Aelbrecht L, Dewaele S, Vandewalle J, Goossens E, Verbanck S, Boyen F, Eggermont M, De Commer L, De Rycke R, De Bruyne M, Tito R, Ballegeer M, Vandevyver S, Velho T, Moita LF, Hochepied T, De Bosscher K, Raes J, Van Immerseel F, Beyaert R, Libert C. Souffriau J, et al. Among authors: eggermont m. EMBO Mol Med. 2020 Oct 7;12(10):e11917. doi: 10.15252/emmm.201911917. Epub 2020 Sep 11. EMBO Mol Med. 2020. PMID: 32914580 Free PMC article.
15 results