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Schistosome Sulfotransferases: Mode of Action, Expression and Localization.
Guzman MA, Rugel A, Alwan SN, Tarpley R, Taylor AB, Chevalier FD, Wendt GR, Collins JJ 3rd, Anderson TJC, McHardy SF, LoVerde PT. Guzman MA, et al. Pharmaceutics. 2022 Jul 6;14(7):1416. doi: 10.3390/pharmaceutics14071416. Pharmaceutics. 2022. PMID: 35890311 Free PMC article.
Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?
Rugel AR, Guzman MA, Taylor AB, Chevalier FD, Tarpley RS, McHardy SF, Cao X, Holloway SP, Anderson TJC, Hart PJ, LoVerde PT. Rugel AR, et al. Among authors: guzman ma. Int J Parasitol Drugs Drug Resist. 2020 Aug;13:8-15. doi: 10.1016/j.ijpddr.2020.04.001. Epub 2020 Apr 10. Int J Parasitol Drugs Drug Resist. 2020. PMID: 32315953 Free PMC article.
Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.
Chevalier FD, Le Clec'h W, McDew-White M, Menon V, Guzman MA, Holloway SP, Cao X, Taylor AB, Kinung'hi S, Gouvras AN, Webster BL, Webster JP, Emery AM, Rollinson D, Garba Djirmay A, Al Mashikhi KM, Al Yafae S, Idris MA, Moné H, Mouahid G, Hart PJ, LoVerde PT, Anderson TJC. Chevalier FD, et al. Among authors: guzman ma. PLoS Pathog. 2019 Oct 25;15(10):e1007881. doi: 10.1371/journal.ppat.1007881. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31652296 Free PMC article.