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Tetrazole-based inhibitors of the bacterial enzyme N-succinyl-l,l-2,6-diaminopimelic acid desuccinylase as potential antibiotics.
Bioorg Med Chem Lett. 2023 Mar 1;83:129177. doi: 10.1016/j.bmcl.2023.129177. Epub 2023 Feb 9.
Bioorg Med Chem Lett. 2023.
PMID: 36764468
Cyclobutanone Inhibitors of Diaminopimelate Desuccinylase (DapE) as Potential New Antibiotics.
Habeeb Mohammad TS, Kelley EH, Reidl CT, Konczak K, Beulke M, Javier J, Olsen KW, Becker DP.
Habeeb Mohammad TS, et al. Among authors: beulke m.
Int J Mol Sci. 2024 Jan 22;25(2):1339. doi: 10.3390/ijms25021339.
Int J Mol Sci. 2024.
PMID: 38279338
Free PMC article.
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Biochemical and Structural Analysis of the Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii.
Kelley EH, Minasov G, Konczak K, Shuvalova L, Brunzelle JS, Shukla S, Beulke M, Thabthimthong T, Olsen KW, Inniss NL, Satchell KJF, Becker DP.
Kelley EH, et al. Among authors: beulke m.
ACS Omega. 2024 Jan 8;9(3):3905-3915. doi: 10.1021/acsomega.3c08231. eCollection 2024 Jan 23.
ACS Omega. 2024.
PMID: 38284080
Free PMC article.
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