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Polyenylpyrrole derivatives inhibit NLRP3 inflammasome activation and inflammatory mediator expression by reducing reactive oxygen species production and mitogen-activated protein kinase activation.
Hua KF, Chou JC, Lam Y, Tasi YL, Chen A, Ka SM, Fang Z, Liu ML, Yang FL, Yang YL, Chiu YC, Wu SH. Hua KF, et al. Among authors: liu ml. PLoS One. 2013 Oct 7;8(10):e76754. doi: 10.1371/journal.pone.0076754. eCollection 2013. PLoS One. 2013. PMID: 24116148 Free PMC article.