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Page 1
Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.
White WB, Saag KG, Becker MA, Borer JS, Gorelick PB, Whelton A, Hunt B, Castillo M, Gunawardhana L; CARES Investigators. White WB, et al. N Engl J Med. 2018 Mar 29;378(13):1200-1210. doi: 10.1056/NEJMoa1710895. Epub 2018 Mar 12. N Engl J Med. 2018. PMID: 29527974 Free article. Clinical Trial.
The worthless remains of a physician's calling: Max Weber, William Osler, and the last virtue of physicians.
Nussbaum AM. Nussbaum AM. Theor Med Bioeth. 2018 Dec;39(6):419-429. doi: 10.1007/s11017-018-9470-z. Theor Med Bioeth. 2018. PMID: 30387036
On the centenary of Max Weber's "Science as a Vocation," his essay still performs interpretative work. ...
On the centenary of Max Weber's "Science as a Vocation," his essay still performs interpretative work. ...
Structural insights into the mechanism of archaellar rotational switching.
Altegoer F, Quax TEF, Weiland P, Nußbaum P, Giammarinaro PI, Patro M, Li Z, Oesterhelt D, Grininger M, Albers SV, Bange G. Altegoer F, et al. Nat Commun. 2022 May 23;13(1):2857. doi: 10.1038/s41467-022-30358-9. Nat Commun. 2022. PMID: 35606361 Free PMC article.
Emergence of fractal geometries in the evolution of a metabolic enzyme.
Sendker FL, Lo YK, Heimerl T, Bohn S, Persson LJ, Mais CN, Sadowska W, Paczia N, Nußbaum E, Del Carmen Sánchez Olmos M, Forchhammer K, Schindler D, Erb TJ, Benesch JLP, Marklund EG, Bange G, Schuller JM, Hochberg GKA. Sendker FL, et al. Nature. 2024 Apr;628(8009):894-900. doi: 10.1038/s41586-024-07287-2. Epub 2024 Apr 10. Nature. 2024. PMID: 38600380 Free PMC article.
Benzo-fused Tri[8]annulenes as Molecular Models of Cubic Graphite.
Ejlli B, Nußbaum P, Rominger F, Freudenberg J, Bunz UHF, Müllen K. Ejlli B, et al. Angew Chem Int Ed Engl. 2021 Sep 6;60(37):20220-20224. doi: 10.1002/anie.202106233. Epub 2021 Aug 6. Angew Chem Int Ed Engl. 2021. PMID: 34156743 Free PMC article.
Maturation of Platelet Function During Murine Fetal Development In Vivo.
Margraf A, Nussbaum C, Rohwedder I, Klapproth S, Kurz ARM, Florian A, Wiebking V, Pircher J, Pruenster M, Immler R, Dietzel S, Kremer L, Kiefer F, Moser M, Flemmer AW, Quackenbush E, von Andrian UH, Sperandio M. Margraf A, et al. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1076-1086. doi: 10.1161/ATVBAHA.116.308464. Epub 2017 Apr 20. Arterioscler Thromb Vasc Biol. 2017. PMID: 28428216
Effects of back-support exoskeleton use on trunk neuromuscular control during repetitive lifting: A dynamical systems analysis.
Madinei S, Kim S, Srinivasan D, Nussbaum MA. Madinei S, et al. J Biomech. 2021 Jun 23;123:110501. doi: 10.1016/j.jbiomech.2021.110501. Epub 2021 May 8. J Biomech. 2021. PMID: 34000644
Eighteen participants (gender-balanced) completed four minutes of repetitive lifting in nine different conditions, involving symmetric and asymmetric postures when using the BSEs (along with no BSE as a control condition). Maximum Lyapunov exponents (short-term: lambda(max …
Eighteen participants (gender-balanced) completed four minutes of repetitive lifting in nine different conditions, involving symmetric and a …
Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses.
Suvilesh KN, Nussbaum YI, Radhakrishnan V, Manjunath Y, Avella DM, Staveley-O'Carroll KF, Kimchi ET, Chaudhuri AA, Shyu CR, Li G, Pantel K, Warren WC, Mitchem JB, Kaifi JT. Suvilesh KN, et al. Mol Cancer. 2022 Mar 12;21(1):73. doi: 10.1186/s12943-022-01553-5. Mol Cancer. 2022. PMID: 35279152 Free PMC article.
Blockade of MYC, which has a known role in drug resistance, was performed with a MYC/MAX dimerization inhibitor (10058-F4). RESULTS: Out of ten ptPDX, two (20%) stable liquid biopsy CDX mouse models were generated. ...MYC target genes and c-MYC protein were upregulated in …
Blockade of MYC, which has a known role in drug resistance, was performed with a MYC/MAX dimerization inhibitor (10058-F4). RESULTS: …
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.
Nussbaum C, Bannenberg S, Keul P, Gräler MH, Gonçalves-de-Albuquerque CF, Korhonen H, von Wnuck Lipinski K, Heusch G, de Castro Faria Neto HC, Rohwedder I, Göthert JR, Prasad VP, Haufe G, Lange-Sperandio B, Offermanns S, Sperandio M, Levkau B. Nussbaum C, et al. Nat Commun. 2015 Apr 2;6:6416. doi: 10.1038/ncomms7416. Nat Commun. 2015. PMID: 25832730 Free PMC article.
Recapitulation of HDV infection in a fully permissive hepatoma cell line allows efficient drug evaluation.
Lempp FA, Schlund F, Rieble L, Nussbaum L, Link C, Zhang Z, Ni Y, Urban S. Lempp FA, et al. Nat Commun. 2019 May 22;10(1):2265. doi: 10.1038/s41467-019-10211-2. Nat Commun. 2019. PMID: 31118422 Free PMC article.
Evaluation of antiviral drugs shows that the entry inhibitor Myrcludex B (IC(50): 1.4 nM) and interferon-alpha (IC(50): 28 IU/ml, but max. 60-80% inhibition) interfere with primary infection. Lonafarnib inhibits virus secretion (IC(50): 36 nM) but leads to a substantial in …
Evaluation of antiviral drugs shows that the entry inhibitor Myrcludex B (IC(50): 1.4 nM) and interferon-alpha (IC(50): 28 IU/ml, but max …
18 results