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Page 1
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R; International Parkinson's Disease Genomics Consortium (IPDGC); Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI); 23andMe; GenePD; NeuroGenetics Research Consortium (NGRC); Hussman Institute of Human Genomics (HIHG); Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC); Greek Parkinson's Disease Consortium; Alzheimer Genetic Analysis Group; Ikram MA, Ioannidis JP, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB. Nalls MA, et al. Nat Genet. 2014 Sep;46(9):989-93. doi: 10.1038/ng.3043. Epub 2014 Jul 27. Nat Genet. 2014. PMID: 25064009 Free PMC article.
Liquid Phase Separation Controlled by pH.
Adame-Arana O, Weber CA, Zaburdaev V, Prost J, Jülicher F. Adame-Arana O, et al. Biophys J. 2020 Oct 20;119(8):1590-1605. doi: 10.1016/j.bpj.2020.07.044. Epub 2020 Sep 16. Biophys J. 2020. PMID: 33010236 Free PMC article.
We consider the simple case in which interactions are captured by Flory-Huggins interaction parameters corresponding to Debye screening lengths shorter than a nanometer, which is relevant to proteins inside biological cells under physiological conditions. ...
We consider the simple case in which interactions are captured by Flory-Huggins interaction parameters corresponding to Debye screeni …
The Global ALPL gene variant classification project: Dedicated to deciphering variants.
Farman MR, Rehder C, Malli T, Rockman-Greenberg C, Dahir K, Martos-Moreno GÁ, Linglart A, Ozono K, Seefried L, Del Angel G, Webersinke G, Barbazza F, John LK, Delana Mudiyanselage SMA, Högler F, Nading EB, Huggins E, Rush ET, El-Gazzar A, Kishnani PS, Högler W. Farman MR, et al. Bone. 2024 Jan;178:116947. doi: 10.1016/j.bone.2023.116947. Epub 2023 Oct 26. Bone. 2024. PMID: 37898381 Free article.
New theoretical investigations of the photodissociation of ozone in the Hartley, Huggins, Chappuis, and Wulf bands.
Grebenshchikov SY, Qu ZW, Zhu H, Schinke R. Grebenshchikov SY, et al. Phys Chem Chem Phys. 2007 May 7;9(17):2044-64. doi: 10.1039/b701020f. Epub 2007 Mar 15. Phys Chem Chem Phys. 2007. PMID: 17464386 Review.
We review recent theoretical studies of the photodissociation of ozone in the wavelength region from 200 nm to 1100 nm comprising four major absorption bands: Hartley and Huggins (near ultraviolet), Chappuis (visible), and Wulf (near infrared). ...
We review recent theoretical studies of the photodissociation of ozone in the wavelength region from 200 nm to 1100 nm comprising four major …
Time-crystalline eigenstate order on a quantum processor.
Mi X, Ippoliti M, Quintana C, Greene A, Chen Z, Gross J, Arute F, Arya K, Atalaya J, Babbush R, Bardin JC, Basso J, Bengtsson A, Bilmes A, Bourassa A, Brill L, Broughton M, Buckley BB, Buell DA, Burkett B, Bushnell N, Chiaro B, Collins R, Courtney W, Debroy D, Demura S, Derk AR, Dunsworth A, Eppens D, Erickson C, Farhi E, Fowler AG, Foxen B, Gidney C, Giustina M, Harrigan MP, Harrington SD, Hilton J, Ho A, Hong S, Huang T, Huff A, Huggins WJ, Ioffe LB, Isakov SV, Iveland J, Jeffrey E, Jiang Z, Jones C, Kafri D, Khattar T, Kim S, Kitaev A, Klimov PV, Korotkov AN, Kostritsa F, Landhuis D, Laptev P, Lee J, Lee K, Locharla A, Lucero E, Martin O, McClean JR, McCourt T, McEwen M, Miao KC, Mohseni M, Montazeri S, Mruczkiewicz W, Naaman O, Neeley M, Neill C, Newman M, Niu MY, O'Brien TE, Opremcak A, Ostby E, Pato B, Petukhov A, Rubin NC, Sank D, Satzinger KJ, Shvarts V, Su Y, Strain D, Szalay M, Trevithick MD, Villalonga B, White T, Yao ZJ, Yeh P, Yoo J, Zalcman A, Neven H, Boixo S, Smelyanskiy V, Megrant A, Kelly J, Chen Y, Sondhi SL, Moessner R, Kechedzhi K, Khemani V, Roushan P. Mi X, et al. Nature. 2022 Jan;601(7894):531-536. doi: 10.1038/s41586-021-04257-w. Epub 2021 Nov 30. Nature. 2022. PMID: 34847568 Free PMC article.
The Huggins band of ozone: unambiguous electronic and vibrational assignment.
Qu ZW, Zhu H, Tashiro M, Schinke R, Farantos SC. Qu ZW, et al. J Chem Phys. 2004 Apr 15;120(15):6811-4. doi: 10.1063/1.1711589. J Chem Phys. 2004. PMID: 15267579
The Huggins band of ozone is investigated by means of exact dynamics calculations using a new (diabatic) potential energy surface for the (1)B(2) state. The remarkable agreement with the measured spectrum strongly suggests that the Huggins band is due to the two C(s …
The Huggins band of ozone is investigated by means of exact dynamics calculations using a new (diabatic) potential energy surface for …
Enhanced Biopharmaceutical Performance of Rivaroxaban through Polymeric Amorphous Solid Dispersion.
Metre S, Mukesh S, Samal SK, Chand M, Sangamwar AT. Metre S, et al. Mol Pharm. 2018 Feb 5;15(2):652-668. doi: 10.1021/acs.molpharmaceut.7b01027. Epub 2018 Jan 16. Mol Pharm. 2018. PMID: 29287144
Therefore, the role of P-gp inhibiting polymers in enhancing the biopharmaceutical performance of RXB by preparing polymeric amorphous solid dispersion and subsequent improvement in solubility and permeability was investigated. Initially, solubility parameter and Flory-Huggins …
Therefore, the role of P-gp inhibiting polymers in enhancing the biopharmaceutical performance of RXB by preparing polymeric amorphous solid …
Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates.
Fritsch AW, Diaz-Delgadillo AF, Adame-Arana O, Hoege C, Mittasch M, Kreysing M, Leaver M, Hyman AA, Jülicher F, Weber CA. Fritsch AW, et al. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2102772118. doi: 10.1073/pnas.2102772118. Proc Natl Acad Sci U S A. 2021. PMID: 34507991 Free PMC article.
Strikingly, this temperature response can be captured by in vivo phase diagrams that are well described by a Flory-Huggins model at thermodynamic equilibrium. This finding is surprising due to active processes in a living cell. ...
Strikingly, this temperature response can be captured by in vivo phase diagrams that are well described by a Flory-Huggins model at t …
Effects of Heat Acclimatization, Heat Acclimation, and Intermittent Exercise Heat Training on Time-Trial Performance.
Sekiguchi Y, Benjamin CL, Manning CN, Struder JF, Armstrong LE, Lee EC, Huggins RA, Stearns RL, Distefano LJ, Casa DJ. Sekiguchi Y, et al. Sports Health. 2022 Sep-Oct;14(5):694-701. doi: 10.1177/19417381211050643. Epub 2021 Oct 27. Sports Health. 2022. PMID: 34706597 Free PMC article.
Participants were then divided into 3 groups and completed IHT either twice per week (IHT(MAX)), once per week (IHT(MIN)), or not at all (IHT(CON)) over an 8-week period. ...Additionally, IHT(MAX) (-2.2% 4.2%) was faster than IHT(CON) (3.6% 6.9%) (P = 0.05) at post- …
Participants were then divided into 3 groups and completed IHT either twice per week (IHT(MAX)), once per week (IHT(MIN)), or not at …
28 results