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The protease associated (PA) domain in ScpA from Streptococcus pyogenes plays a role in substrate recruitment.
McKenna S, Aylward F, Miliara X, Lau RJ, Huemer CB, Giblin SP, Huse KK, Liang M, Reeves L, Pearson M, Xu Y, Rouse SL, Pease JE, Sriskandan S, Kagawa TF, Cooney J, Matthews S. McKenna S, et al. Among authors: pearson m. Biochim Biophys Acta Proteins Proteom. 2023 Nov 1;1871(6):140946. doi: 10.1016/j.bbapap.2023.140946. Epub 2023 Aug 9. Biochim Biophys Acta Proteins Proteom. 2023. PMID: 37562488 Free article.
Bacterial genotypic and patient risk factors for adverse outcomes in Escherichia coli bloodstream infections: a prospective molecular epidemiological study.
Jauneikaite E, Honeyford K, Blandy O, Mosavie M, Pearson M, Ramzan FA, Ellington MJ, Parkhill J, Costelloe CE, Woodford N, Sriskandan S. Jauneikaite E, et al. Among authors: pearson m. J Antimicrob Chemother. 2022 May 29;77(6):1753-1761. doi: 10.1093/jac/dkac071. J Antimicrob Chemother. 2022. PMID: 35265995 Free PMC article.
Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes.
McKenna S, Malito E, Rouse SL, Abate F, Bensi G, Chiarot E, Micoli F, Mancini F, Gomes Moriel D, Grandi G, Mossakowska D, Pearson M, Xu Y, Pease J, Sriskandan S, Margarit I, Bottomley MJ, Matthews S. McKenna S, et al. Among authors: pearson m. Comput Struct Biotechnol J. 2020 Mar 13;18:650-660. doi: 10.1016/j.csbj.2020.03.004. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32257048 Free PMC article.
Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study.
Lynskey NN, Jauneikaite E, Li HK, Zhi X, Turner CE, Mosavie M, Pearson M, Asai M, Lobkowicz L, Chow JY, Parkhill J, Lamagni T, Chalker VJ, Sriskandan S. Lynskey NN, et al. Among authors: pearson m. Lancet Infect Dis. 2019 Nov;19(11):1209-1218. doi: 10.1016/S1473-3099(19)30446-3. Epub 2019 Sep 10. Lancet Infect Dis. 2019. PMID: 31519541 Free PMC article.