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marie bach
(1 results)?
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species.
Nat Commun. 2024 Mar 18;15(1):2436. doi: 10.1038/s41467-024-46538-8.
Nat Commun. 2024.
PMID: 38499535
Free PMC article.
Selective Inhibition of the Hsp90α Isoform.
Mishra SJ, Khandelwal A, Banerjee M, Balch M, Peng S, Davis RE, Merfeld T, Munthali V, Deng J, Matts RL, Blagg BSJ.
Mishra SJ, et al. Among authors: balch m.
Angew Chem Int Ed Engl. 2021 May 3;60(19):10547-10551. doi: 10.1002/anie.202015422. Epub 2021 Mar 26.
Angew Chem Int Ed Engl. 2021.
PMID: 33621416
Free PMC article.
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HtrA1 prevents and reverses α-synuclein aggregation, rendering it non-toxic and seeding incompetent.
Chen S, Puri A, Bell B, Fritsche J, Palacios H, Balch M, Sprunger M, Howard M, Patterson J, Patti G, Davis A, Jackrel M.
Chen S, et al. Among authors: balch m.
Res Sq [Preprint]. 2023 Aug 22:rs.3.rs-2570571. doi: 10.21203/rs.3.rs-2570571/v1.
Res Sq. 2023.
PMID: 37674720
Free PMC article.
Updated.
Preprint.
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Proteomic Profiling of Hsp90 Inhibitors.
Voruganti S, Kline JT, Balch MJ, Rogers J, Matts RL, Hartson SD.
Voruganti S, et al. Among authors: balch mj.
Methods Mol Biol. 2018;1709:139-162. doi: 10.1007/978-1-4939-7477-1_11.
Methods Mol Biol. 2018.
PMID: 29177657
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Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor.
Khandelwal A, Kent CN, Balch M, Peng S, Mishra SJ, Deng J, Day VW, Liu W, Subramanian C, Cohen M, Holzbeierlein JM, Matts R, Blagg BSJ.
Khandelwal A, et al. Among authors: balch m.
Nat Commun. 2018 Jan 30;9(1):425. doi: 10.1038/s41467-017-02013-1.
Nat Commun. 2018.
PMID: 29382832
Free PMC article.
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Structure-Activity Relationship Study of Tertiary Alcohol Hsp90α-Selective Inhibitors with Novel Binding Mode.
Mishra SJ, Reynolds TS, Merfeld T, Balch M, Peng S, Deng J, Matts R, Blagg BSJ.
Mishra SJ, et al. Among authors: balch m.
ACS Med Chem Lett. 2022 Nov 4;13(12):1870-1878. doi: 10.1021/acsmedchemlett.2c00327. eCollection 2022 Dec 8.
ACS Med Chem Lett. 2022.
PMID: 36518703
Free PMC article.
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High-throughput screen of natural product libraries for hsp90 inhibitors.
Davenport J, Balch M, Galam L, Girgis A, Hall J, Blagg BS, Matts RL.
Davenport J, et al. Among authors: balch m.
Biology (Basel). 2014 Feb 10;3(1):101-38. doi: 10.3390/biology3010101.
Biology (Basel). 2014.
PMID: 24833337
Free PMC article.
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