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Diversely Functionalised Cytochalasins through Mutasynthesis and Semi-Synthesis.
Wang C, Lambert C, Hauser M, Deuschmann A, Zeilinger C, Rottner K, Stradal TEB, Stadler M, Skellam EJ, Cox RJ. Wang C, et al. Among authors: hauser m. Chemistry. 2020 Oct 27;26(60):13578-13583. doi: 10.1002/chem.202002241. Epub 2020 Sep 17. Chemistry. 2020. PMID: 32484589 Free PMC article.
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Reinke PYA, de Souza EE, Günther S, Falke S, Lieske J, Ewert W, Loboda J, Herrmann A, Rahmani Mashhour A, Karničar K, Usenik A, Lindič N, Sekirnik A, Botosso VF, Santelli GMM, Kapronezai J, de Araújo MV, Silva-Pereira TT, Filho AFS, Tavares MS, Flórez-Álvarez L, de Oliveira DBL, Durigon EL, Giaretta PR, Heinemann MB, Hauser M, Seychell B, Böhler H, Rut W, Drag M, Beck T, Cox R, Chapman HN, Betzel C, Brehm W, Hinrichs W, Ebert G, Latham SL, Guimarães AMS, Turk D, Wrenger C, Meents A. Reinke PYA, et al. Among authors: hauser m. Commun Biol. 2023 Oct 18;6(1):1058. doi: 10.1038/s42003-023-05317-9. Commun Biol. 2023. PMID: 37853179 Free PMC article.