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Page 1
New Insights on the Mechanisms of Disease Course Variability in ALS from Mutant SOD1 Mouse Models.
Brain Pathol. 2016 Mar;26(2):237-47. doi: 10.1111/bpa.12351.
Brain Pathol. 2016.
PMID: 26780365
Free PMC article.
Review.
Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model.
Apolloni S, Fabbrizio P, Amadio S, Napoli G, Freschi M, Sironi F, Pevarello P, Tarroni P, Liberati C, Bendotti C, Volonté C.
Apolloni S, et al. Among authors: freschi m.
Int J Mol Sci. 2021 Sep 30;22(19):10649. doi: 10.3390/ijms221910649.
Int J Mol Sci. 2021.
PMID: 34638992
Free PMC article.
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Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model.
De Paola M, Sestito SE, Mariani A, Memo C, Fanelli R, Freschi M, Bendotti C, Calabrese V, Peri F.
De Paola M, et al. Among authors: freschi m.
Pharmacol Res. 2016 Jan;103:180-7. doi: 10.1016/j.phrs.2015.11.020. Epub 2015 Nov 27.
Pharmacol Res. 2016.
PMID: 26640075
Free article.
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A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Immune Dysregulation.
Vallarola A, Tortarolo M, De Gioia R, Iamele L, de Jonge H, de Nola G, Bovio E, Pasetto L, Bonetto V, Freschi M, Bendotti C, Gherardi E.
Vallarola A, et al. Among authors: freschi m.
Int J Mol Sci. 2020 Nov 12;21(22):8542. doi: 10.3390/ijms21228542.
Int J Mol Sci. 2020.
PMID: 33198383
Free PMC article.
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Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.
Pasetto L, Pozzi S, Castelnovo M, Basso M, Estevez AG, Fumagalli S, De Simoni MG, Castellaneta V, Bigini P, Restelli E, Chiesa R, Trojsi F, Monsurrò MR, Callea L, Malešević M, Fischer G, Freschi M, Tortarolo M, Bendotti C, Bonetto V.
Pasetto L, et al. Among authors: freschi m.
J Neurosci. 2017 Feb 8;37(6):1413-1427. doi: 10.1523/JNEUROSCI.2462-16.2016. Epub 2016 Dec 23.
J Neurosci. 2017.
PMID: 28011744
Free PMC article.
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ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin.
Sassone J, Taiana M, Lombardi R, Porretta-Serapiglia C, Freschi M, Bonanno S, Marcuzzo S, Caravello F, Bendotti C, Lauria G.
Sassone J, et al. Among authors: freschi m.
Hum Mol Genet. 2016 Apr 15;25(8):1588-99. doi: 10.1093/hmg/ddw035. Epub 2016 Feb 9.
Hum Mol Genet. 2016.
PMID: 26908600
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Multiple intracerebroventricular injections of human umbilical cord mesenchymal stem cells delay motor neurons loss but not disease progression of SOD1G93A mice.
Sironi F, Vallarola A, Violatto MB, Talamini L, Freschi M, De Gioia R, Capelli C, Agostini A, Moscatelli D, Tortarolo M, Bigini P, Introna M, Bendotti C.
Sironi F, et al. Among authors: freschi m.
Stem Cell Res. 2017 Dec;25:166-178. doi: 10.1016/j.scr.2017.11.005. Epub 2017 Nov 10.
Stem Cell Res. 2017.
PMID: 29154076
Free article.
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