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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 4
2005 1
2006 1
2007 2
2008 5
2009 7
2010 9
2011 9
2012 5
2013 9
2014 7
2015 15
2016 14
2017 4
2018 3
2019 10
2020 4
2021 14
2022 7
2023 6
2024 6

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129 results

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Page 1
Targeted protein degradation: expanding the toolbox.
Schapira M, Calabrese MF, Bullock AN, Crews CM. Schapira M, et al. Nat Rev Drug Discov. 2019 Dec;18(12):949-963. doi: 10.1038/s41573-019-0047-y. Epub 2019 Oct 30. Nat Rev Drug Discov. 2019. PMID: 31666732
Methods for computer-assisted PROTAC design.
Rovers E, Schapira M. Rovers E, et al. Among authors: schapira m. Methods Enzymol. 2023;690:311-340. doi: 10.1016/bs.mie.2023.06.020. Epub 2023 Jul 21. Methods Enzymol. 2023. PMID: 37858533 Review.
Targeting non-bromodomain chromatin readers.
Arrowsmith CH, Schapira M. Arrowsmith CH, et al. Among authors: schapira m. Nat Struct Mol Biol. 2019 Oct;26(10):863-869. doi: 10.1038/s41594-019-0290-2. Epub 2019 Oct 3. Nat Struct Mol Biol. 2019. PMID: 31582844 Review.
Probing the epigenome.
Huston A, Arrowsmith CH, Knapp S, Schapira M. Huston A, et al. Among authors: schapira m. Nat Chem Biol. 2015 Aug;11(8):542-5. doi: 10.1038/nchembio.1871. Nat Chem Biol. 2015. PMID: 26196765 No abstract available.
Chemical Inhibition of Protein Methyltransferases.
Schapira M. Schapira M. Cell Chem Biol. 2016 Sep 22;23(9):1067-1076. doi: 10.1016/j.chembiol.2016.07.014. Epub 2016 Aug 25. Cell Chem Biol. 2016. PMID: 27569753 Free article. Review.
Ten simple rules for open human health research.
Bafeta A, Bobe J, Clucas J, Gonsalves PP, Gruson-Daniel C, Hudson KL, Klein A, Krishnakumar A, McCollister-Slipp A, Lindner AB, Misevic D, Naslund JA, Nebeker C, Nikolaidis A, Pasquetto I, Sanchez G, Schapira M, Scheininger T, Schoeller F, Sólon Heinsfeld A, Taddei F. Bafeta A, et al. Among authors: schapira m. PLoS Comput Biol. 2020 Sep 3;16(9):e1007846. doi: 10.1371/journal.pcbi.1007846. eCollection 2020 Sep. PLoS Comput Biol. 2020. PMID: 32881878 Free PMC article. No abstract available.
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization.
Dilworth D, Hanley RP, Ferreira de Freitas R, Allali-Hassani A, Zhou M, Mehta N, Marunde MR, Ackloo S, Carvalho Machado RA, Khalili Yazdi A, Owens DDG, Vu V, Nie DY, Alqazzaz M, Marcon E, Li F, Chau I, Bolotokova A, Qin S, Lei M, Liu Y, Szewczyk MM, Dong A, Kazemzadeh S, Abramyan T, Popova IK, Hall NW, Meiners MJ, Cheek MA, Gibson E, Kireev D, Greenblatt JF, Keogh MC, Min J, Brown PJ, Vedadi M, Arrowsmith CH, Barsyte-Lovejoy D, James LI, Schapira M. Dilworth D, et al. Among authors: schapira m. Nat Chem Biol. 2022 Jan;18(1):56-63. doi: 10.1038/s41589-021-00898-0. Epub 2021 Nov 15. Nat Chem Biol. 2022. PMID: 34782742 Free PMC article.
Target 2035 - an update on private sector contributions.
Ackloo S, Antolin AA, Bartolome JM, Beck H, Bullock A, Betz UAK, Böttcher J, Brown PJ, Chaturvedi M, Crisp A, Daniels D, Dreher J, Edfeldt K, Edwards AM, Egner U, Elkins J, Fischer C, Glendorf T, Goldberg S, Hartung IV, Hillisch A, Homan E, Knapp S, Köster M, Krämer O, Llaveria J, Lessel U, Lindemann S, Linderoth L, Matsui H, Michel M, Montel F, Mueller-Fahrnow A, Müller S, Owen DR, Saikatendu KS, Santhakumar V, Sanderson W, Scholten C, Schapira M, Sharma S, Shireman B, Sundström M, Todd MH, Tredup C, Venable J, Willson TM, Arrowsmith CH. Ackloo S, et al. Among authors: schapira m. RSC Med Chem. 2023 Mar 16;14(6):1002-1011. doi: 10.1039/d2md00441k. eCollection 2023 Jun 22. RSC Med Chem. 2023. PMID: 37360399 Free PMC article.
Target 2035 - update on the quest for a probe for every protein.
Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Saikatendu KS, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workman P, Arrowsmith CH. Müller S, et al. Among authors: schapira m. RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27. RSC Med Chem. 2021. PMID: 35211674 Free PMC article.
129 results