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Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles.
Piret JP, Bondarenko OM, Boyles MSP, Himly M, Ribeiro AR, Benetti F, Smal C, Lima B, Potthoff A, Simion M, Dumortier E, Leite PEC, Balottin LB, Granjeiro JM, Ivask A, Kahru A, Radauer-Preiml I, Tischler U, Duschl A, Saout C, Anguissola S, Haase A, Jacobs A, Nelissen I, Misra SK, Toussaint O. Piret JP, et al. Among authors: boyles msp. Arch Toxicol. 2017 Jun;91(6):2315-2330. doi: 10.1007/s00204-016-1897-2. Epub 2016 Dec 10. Arch Toxicol. 2017. PMID: 27942788
Poly-lactic acid nanoparticles (PLA-NP) promote physiological modifications in lung epithelial cells and are internalized by clathrin-coated pits and lipid rafts.
da Luz CM, Boyles MS, Falagan-Lotsch P, Pereira MR, Tutumi HR, de Oliveira Santos E, Martins NB, Himly M, Sommer A, Foissner I, Duschl A, Granjeiro JM, Leite PE. da Luz CM, et al. J Nanobiotechnology. 2017 Jan 31;15(1):11. doi: 10.1186/s12951-016-0238-1. J Nanobiotechnology. 2017. PMID: 28143572 Free PMC article.
Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions.
Stoehr LC, Endes C, Radauer-Preiml I, Boyles MS, Casals E, Balog S, Pesch M, Petri-Fink A, Rothen-Rutishauser B, Himly M, Clift MJ, Duschl A. Stoehr LC, et al. Among authors: boyles ms. Part Fibre Toxicol. 2015 Sep 29;12:29. doi: 10.1186/s12989-015-0104-6. Part Fibre Toxicol. 2015. PMID: 26415698 Free PMC article.
Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components.
Boyles MS, Kristl T, Andosch A, Zimmermann M, Tran N, Casals E, Himly M, Puntes V, Huber CG, Lütz-Meindl U, Duschl A. Boyles MS, et al. J Nanobiotechnology. 2015 Nov 18;13:84. doi: 10.1186/s12951-015-0146-9. J Nanobiotechnology. 2015. PMID: 26582370 Free PMC article.
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