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Trem2 expression in microglia is required to maintain normal neuronal bioenergetics during development.
Tagliatti E, Desiato G, Mancinelli S, Bizzotto M, Gagliani MC, Faggiani E, Hernández-Soto R, Cugurra A, Poliseno P, Miotto M, Argüello RJ, Filipello F, Cortese K, Morini R, Lodato S, Matteoli M. Tagliatti E, et al. Among authors: bizzotto m. Immunity. 2024 Jan 9;57(1):86-105.e9. doi: 10.1016/j.immuni.2023.12.002. Epub 2023 Dec 29. Immunity. 2024. PMID: 38159572 Free PMC article.
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.
Scott-Hewitt N, Perrucci F, Morini R, Erreni M, Mahoney M, Witkowska A, Carey A, Faggiani E, Schuetz LT, Mason S, Tamborini M, Bizzotto M, Passoni L, Filipello F, Jahn R, Stevens B, Matteoli M. Scott-Hewitt N, et al. Among authors: bizzotto m. EMBO J. 2020 Aug 17;39(16):e105380. doi: 10.15252/embj.2020105380. Epub 2020 Jul 13. EMBO J. 2020. PMID: 32657463 Free PMC article.