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Showing results for mathe a simons
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Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute.
Cooper CE, Silkstone GGA, Simons M, Rajagopal B, Syrett N, Shaik T, Gretton S, Welbourn E, Bülow L, Eriksson NL, Ronda L, Mozzarelli A, Eke A, Mathe D, Reeder BJ. Cooper CE, et al. Free Radic Biol Med. 2019 Apr;134:106-118. doi: 10.1016/j.freeradbiomed.2018.12.030. Epub 2018 Dec 27. Free Radic Biol Med. 2019. PMID: 30594736 Free PMC article.
Synthesis of nucleoside analogues bearing the five naturally occurring nucleic acid bases built on a 2-oxabicylo[3.1.0]hexane scaffold.
Gagneron J, Gosselin G, Mathé C. Gagneron J, et al. J Org Chem. 2005 Aug 19;70(17):6891-7. doi: 10.1021/jo051047b. J Org Chem. 2005. PMID: 16095310
This sugar was readily obtained from [(3aS,6aS)-2,2-dimethyl-3a,6a-dihydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzyl ether (4) following a Simons-Smith-type cyclopropanation reaction. Finally, glycosylation reactions and deprotection provided the nucleoside analogues. ...
This sugar was readily obtained from [(3aS,6aS)-2,2-dimethyl-3a,6a-dihydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzyl ether (4) following a …