Integrative Analysis of Rhythmicity: From Biology to Urban Environments and Sustainability

Miha Moškon; Tadeja Režen; Matevž Juvančič; Špela Verovšek

doi:10.3390/ijerph20010764

Integrative Analysis of Rhythmicity: From Biology to Urban Environments and Sustainability

Int J Environ Res Public Health. 2022 Dec 31;20(1):764. doi: 10.3390/ijerph20010764.

Authors

Miha Moškon¹, Tadeja Režen², Matevž Juvančič³, Špela Verovšek³

Affiliations

¹ Faculty of Computer and Information Science, University of Ljubljana, 1000 Ljubljana, Slovenia.
² Centre for Functional Genomics and Bio-Chips, Institute for Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
³ Faculty of Architecture, University of Ljubljana, 1000 Ljubljana, Slovenia.

Abstract

From biological to socio-technical systems, rhythmic processes are pervasive in our environment. However, methods for their comprehensive analysis are prevalent only in specific fields that limit the transfer of knowledge across scientific disciplines. This hinders interdisciplinary research and integrative analyses of rhythms across different domains and datasets. In this paper, we review recent developments in cross-disciplinary rhythmicity research, with a focus on the importance of rhythmic analyses in urban planning and biomedical research. Furthermore, we describe the current state of the art of (integrative) computational methods for the investigation of rhythmic data. Finally, we discuss the further potential and propose necessary future developments for cross-disciplinary rhythmicity analysis to foster integration of heterogeneous datasets across different domains, as well as guide data-driven decision making beyond the boundaries of traditional intradisciplinary research, especially in the context of sustainable and healthy cities.

Keywords: circadian clock; computational framework; integrative analyses; rhythmicity analysis; rhythms; sustainability; transferability; urban rhythms.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Biology
Biomedical Research*
Circadian Rhythm*
Cities

Grants and funding

This research was partially supported by the basic research project “Data integration framework for the assessment of sustainable efficiency in Slovene neighbourhoods and settlements” (J5-1798), by the scientific-research program “Pervasive Computing” (P2-0359), by the scientific research program “Functional Genomics and Biotechnology for Health” (P1-0390) and by the scientific-research program “Sustainable planning for the quality living space” (P5-0068), all financed by the Slovenian Research Agency. This research was partially supported by the University of Ljubljana Development Fund. The funding sources had no role in the design of the study or collection, analysis, or interpretation of data, nor in writing the manuscript.