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TC-G 1008 facilitates epileptogenesis by acting selectively at the GPR39 receptor but non-selectively activates CREB in the hippocampus of pentylenetetrazole-kindled mice.
Doboszewska U, Socała K, Pieróg M, Nieoczym D, Sawicki J, Szafarz M, Gawel K, Rafało-Ulińska A, Sajnóg A, Wyska E, Esguerra CV, Szewczyk B, Maćkowiak M, Barałkiewicz D, Mlyniec K, Nowak G, Sowa I, Wlaź P. Doboszewska U, et al. Among authors: pierog m. Cell Mol Life Sci. 2023 Apr 25;80(5):133. doi: 10.1007/s00018-023-04766-z. Cell Mol Life Sci. 2023. PMID: 37185787 Free PMC article.
Alterations of Serum Magnesium Concentration in Animal Models of Seizures and Epilepsy-The Effects of Treatment with a GPR39 Agonist and Knockout of the Gpr39 Gene.
Doboszewska U, Sawicki J, Sajnóg A, Szopa A, Serefko A, Socała K, Pieróg M, Nieoczym D, Mlyniec K, Nowak G, Barałkiewicz D, Sowa I, Wlaź P. Doboszewska U, et al. Among authors: pierog m. Cells. 2022 Jun 21;11(13):1987. doi: 10.3390/cells11131987. Cells. 2022. PMID: 35805072 Free PMC article.
N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug.
Kamiński K, Socała K, Zagaja M, Andres-Mach M, Abram M, Jakubiec M, Pieróg M, Nieoczym D, Rapacz A, Gawel K, Esguerra CV, Latacz G, Lubelska A, Szulczyk B, Szewczyk A, Łuszczki JJ, Wlaź P. Kamiński K, et al. Among authors: pierog m. Neurotherapeutics. 2020 Jan;17(1):309-328. doi: 10.1007/s13311-019-00773-w. Neurotherapeutics. 2020. PMID: 31486023 Free PMC article.
Dietary Zinc Differentially Regulates the Effects of the GPR39 Receptor Agonist, TC-G 1008, in the Maximal Electroshock Seizure Test and Pentylenetetrazole-Kindling Model of Epilepsy.
Doboszewska U, Socała K, Pieróg M, Nieoczym D, Sawicki J, Sajnóg A, Szewczyk B, Mlyniec K, Sowa I, Barałkiewicz D, Wlaź P. Doboszewska U, et al. Among authors: pierog m. Cells. 2023 Jan 9;12(2):264. doi: 10.3390/cells12020264. Cells. 2023. PMID: 36672199 Free PMC article.
KA-11, a Novel Pyrrolidine-2,5-dione Derived Broad-Spectrum Anticonvulsant: Its Antiepileptogenic, Antinociceptive Properties and in Vitro Characterization.
Socała K, Mogilski S, Pieróg M, Nieoczym D, Abram M, Szulczyk B, Lubelska A, Latacz G, Doboszewska U, Wlaź P, Kamiński K. Socała K, et al. Among authors: pierog m. ACS Chem Neurosci. 2019 Jan 16;10(1):636-648. doi: 10.1021/acschemneuro.8b00476. Epub 2018 Oct 10. ACS Chem Neurosci. 2019. PMID: 30247871
21 results