Disclosure of a Promising Lead to Tackle Complicated Skin and Skin Structure Infections: Antimicrobial and Antibiofilm Actions of Peptide PP4-3.1.
Gomes A, Bessa LJ, Fernandes I, Ferraz R, Monteiro C, L Martins MC, Mateus N, Gameiro P, Teixeira C, Gomes P.
Gomes A, et al.
Pharmaceutics. 2021 Nov 19;13(11):1962. doi: 10.3390/pharmaceutics13111962.
Pharmaceutics. 2021.
PMID: 34834377
Free PMC article.
As such, we combined the well-known cosmeceutical pentapeptide-4 (PP4), devoid of antimicrobial action but possessing collagenesis-boosting properties, with the AMP 3.1, to afford the chimeric peptide PP4-3.1. We further produced its N-methyl imidazole derivative, MeIm-PP4 …
As such, we combined the well-known cosmeceutical pentapeptide-4 (PP4), devoid of antimicrobial action but possessing collagenesis-boosting …