Background: Outcomes after sirolimus-eluting stent (SES: Cypher) implantation remained to be elucidated in Japan.
Methods and results: Among 1,070 consecutive angiographic follow-up lesions, 99 lesions underwent target lesion revascularization (TLR) with in-stent restenosis (ISR). Retrospective estimation by multivariate analysis including 50 variables showed that the ostiums of right coronary and left circumflex arteries, hemodialysis, calcification, non-direct stenting, ISR of SES, and non-eccentric lesion were the predictors of TLR. There was no documented late stent thrombosis (LST) among 2,166 lesions and very LST (VLST) among 1,423 lesions.
Conclusion: Further revises are needed to implant SES to these predictive lesions. LST and VLST were very rare.