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TGFβ-Activated USP27X Deubiquitinase Regulates Cell Migration and Chemoresistance via Stabilization of Snail1.
Lambies G, Miceli M, Martínez-Guillamon C, Olivera-Salguero R, Peña R, Frías CP, Calderón I, Atanassov BS, Dent SYR, Arribas J, García de Herreros A, Díaz VM. Lambies G, et al. Among authors: miceli m. Cancer Res. 2019 Jan 1;79(1):33-46. doi: 10.1158/0008-5472.CAN-18-0753. Epub 2018 Oct 19. Cancer Res. 2019. PMID: 30341066 Free PMC article.
Mutations in ACTL6B, coding for a subunit of the neuron-specific chromatin remodeling complex nBAF, cause early onset severe developmental and epileptic encephalopathy with brain hypomyelination and cerebellar atrophy.
Fichera M, Failla P, Saccuzzo L, Miceli M, Salvo E, Castiglia L, Galesi O, Grillo L, Calì F, Greco D, Amato C, Romano C, Elia M. Fichera M, et al. Among authors: miceli m. Hum Genet. 2019 Feb;138(2):187-198. doi: 10.1007/s00439-019-01972-3. Epub 2019 Jan 17. Hum Genet. 2019. PMID: 30656450 Clinical Trial.
Targeting Serotonin 2A and Adrenergic α1 Receptors for Ocular Antihypertensive Agents: Discovery of 3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one Derivatives.
Furlotti G, Alisi MA, Cazzolla N, Ceccacci F, Garrone B, Gasperi T, La Bella A, Leonelli F, Loreto MA, Magarò G, Mangano G, Bettolo RM, Masini E, Miceli M, Migneco LM, Vitiello M. Furlotti G, et al. Among authors: miceli m. ChemMedChem. 2018 Aug 10;13(15):1597-1607. doi: 10.1002/cmdc.201800199. Epub 2018 Jul 9. ChemMedChem. 2018. PMID: 29873449
Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier.
Vázquez-Jiménez L, Garrido M, Miceli M, Prats E, Ferrer-Montiel A, Teixidó M, Jimeno C, Messeguer A. Vázquez-Jiménez L, et al. Among authors: miceli m. Eur J Med Chem. 2016 Nov 10;123:788-802. doi: 10.1016/j.ejmech.2016.08.007. Epub 2016 Aug 6. Eur J Med Chem. 2016. PMID: 27541262