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Liposomal formulation of model pentathiepin improves solubility and stability toward glutathione while preserving anticancer activity.
Arch Pharm (Weinheim). 2023 Oct;356(10):e2300087. doi: 10.1002/ardp.202300087. Epub 2023 Jul 28.
Arch Pharm (Weinheim). 2023.
PMID: 37507825
Comprehensive Evaluation of Biological Effects of Pentathiepins on Various Human Cancer Cell Lines and Insights into Their Mode of Action.
Wolff L, Bandaru SSM, Eger E, Lam HN, Napierkowski M, Baecker D, Schulzke C, Bednarski PJ.
Wolff L, et al. Among authors: napierkowski m.
Int J Mol Sci. 2021 Jul 16;22(14):7631. doi: 10.3390/ijms22147631.
Int J Mol Sci. 2021.
PMID: 34299253
Free PMC article.
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Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells.
Behnisch-Cornwell S, Bandaru SSM, Napierkowski M, Wolff L, Zubair M, Urbainsky C, Lillig C, Schulzke C, Bednarski PJ.
Behnisch-Cornwell S, et al. Among authors: napierkowski m.
ChemMedChem. 2020 Aug 19;15(16):1515-1528. doi: 10.1002/cmdc.202000160. Epub 2020 May 6.
ChemMedChem. 2020.
PMID: 32311219
Free PMC article.
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